His-Bundle and Left Bundle Branch Pacing Papers

Research papers and their abstracts, presented according to key questions they address

What is the risk of heart failure due to conventional pacing?

Conduction System Pacing Associated with Reduced Heart-Failure Hospitalizations and All-Cause Mortality Compared to Traditional Right Ventricular Pacing in the Medicare Population; Pugazhendhi Vijayaraman, MD, FHRS, Colleen Longacre, PhD, MPH, Jordana Kron, MD, Faiz Subzposh, MD, Patrick Zimmerman, PhD Kiah Butler, PhD2, George H. Crossley, MD, Kenneth A. Ellenbogen, MD, FHRS3; https://doi.org/10.1016/j.hrthm.2024.08.052

Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management; Vincenzo Somma MD, Francis J. Ha MBBS(Hons), BMedSc(Hons), Sonny Palmer MBBS, DMedSci, Uwais Mohamed MBBS, Sharad Agarwal MD; Heart Rhythm, Vol 20, Issue 2, February 2023, Pages 282-290

Risk factors for developing pacing induced LV dysfunction: Experience from a tertiary center in the UK; Vijayabharathy Kanthasamy, Nikolaos Papageorgiou, Tomi Bajomo, Christopher Monkhouse, Antonio Creta, Malcolm Finlay, Pier D Lambiase, Phil Moore, Simon Sporton, Mark J Earley, Richard J Schilling, Carl Hayward, Rui Providência, Ross J Hunter, Anthony W Chow, Amal Muthumala; Pacing and Clinical Electrophysiol, 2022 Mar, 45(3):365-373. doi: 10.1111/pace.14442. Epub 2022 Jan 28.

Impact of His bundle pacing on right ventricular performance in patients undergoing permanent pacemaker implantation; Domenico Grieco MD, PhD, Edoardo Bressi MD, Karol Curila MD, PhD, Santosh K. Padala MD, Kamil Sedlacek MD, Jordana Kron MD, Elisa Fedele MD, Oana Ionita MD, Sara Giannuzzi MD, Alessandro Fagagnini MD, Germana Panattoni MD, PhD, Ermenegildo De Ruvo MD, Kenneth A. Ellenbogen MD, Leonardo Calò MD; Pacing and Clinical Electrophysiology: PACE, 23 Apr 2021, DOI: 10.1111/pace.14249

Development of New‐Onset or Progressive Atrial Fibrillation in Patients With Permanent HIS Bundle Pacing Versus Right Ventricular Pacing: Results From the RUSH HBP Registry; Venkatesh Ravi, Dominik Beer, Grzegorz M. Pietrasik, Jillian L. Hanifin, Sara Ooms, Muhammad Talha Ayub, Timothy Larsen, Henry D. Huang, Kousik Krishnan, Richard G. Trohman, Pugazhendhi Vijayaraman, and Parikshit S. Sharma; Journal of the American Heart Association, 11 Nov 2020

Permanent His bundle pacing in patients with congenital complete heart block; Gopi Dandamudi MD, MBA, Joel Simon MD, Oscar Cano MD, Vivak Master MD, Jacob S. Koruth MD, Angela Naperkowski RN, Adam C. Kean MD, Robert Schaller MD, Kenneth A. Ellenbogen MD, Jordana Kron MD, Pugazhendhi Vijayaraman MD; JACC: Clinical Electrophysiology, Available online 24 December 2020

The Prevalence of Pacing-Induced Cardiomyopathy (PICM) in Patients With Long Term Right Ventricular Pacing − Is it a Matter Of Definition?; Gerald Kaye, MBChB, MD, FRACP, Jun Yen Ng, MBBSa, Shameer Ahmed, MBBS, FRACP, Diana Valencia, MBBS, Danielle Harrop, MBBS, Arnold C.T. Ng, MBBS, PhD, FRACP; Heart, Lung and Circulation; July 2019 Volume 28, Issue 7, Pages 1027–1033

His Bundle Pacing; Pugazhendhi Vijayaraman, Mina K. Chung, Gopi Dandamudi, Gaurav A. Upadhyay, Kousik Krishnan, George Crossley, Kristen Bova Campbell, Byron K. Lee, Marwan M. Refaat, Sanjeev Saksena, John D. Fisher, Dhananjaya Lakkireddy and on behalf of the ACC’s Electrophysiology Council; Journal of the American College of Cardiology; Volume 72, Issue 8, August 2018

Clinical Outcomes of His Bundle Pacing Compared to Right Ventricular Pacing; Mohamed Abdelrahman, MD, Faiz A. Subzposh,MD, Dominik Beer,DO, Brendan Durr,DO, Angela Naperkowski, RN, CEPS, CCDS, FHRS, Haiyan Sun, MS, Jess W. Oren, MD, Gopi Dandamudi, MD, FHRS, Pugazhendhi Vijayaraman, MD, FACC, (pvijayaraman1@geisinger.edu) (pvijayaraman@gmail.com); JACC, March, 2018

Patients with long-term permanent pacemakers have a high prevalence of left ventricular dysfunction; Gierula J, et al. J Cardiovasc Med (Hagerstown). 2015

His or para-His pacing preserves left ventricular function in atrioventricular block: a double-blind, randomized, crossover study; Mads B. Kronborg Peter T. Mortensen Steen H. Poulsen Jens C. GerdesHenrik K. Jensen Jens C. Nielsen; EP Europace, Volume 16, Issue 8, 1 August 2014, Pages 1189–1196

Pacing-associated left ventricular dysfunction? Think reprogramming first!, Randomized controlled trial; Gierula J, et al. Heart. 2014

Permanent His Bundle Pacing: Long-Term Lead Performance and Clinical Outcomes; Pugazhendhi Vijayaraman, MD, FHRS, Angela Naperkowski, RN, CEPS, CCDS, FHRS, Faiz A. Subzposh, MD, Mohamed Abdelrahman, MD,, Parikshit S. Sharma, MD, Jess W. Oren, MD, FHRS, Gopi Dandamudi, MD, FHRS, Kenneth A. Ellenbogen, MD, FHRS; DOI: http://dx.doi.org/10.1016/j.hrthm.2017.12.022

His Bundle Pacing Hits the Mainstream at HRS 2017; John Mandrola, MD

Permanent His Bundle Pacing Reduces Mortality/Morbidity In Pacemaker Population Compared to Right Ventricular Pacing; Pugazhendhi Vijayaraman, MD, FHRS, Faiz A. Subzposh, MD, Gopi Dandamudi, MD, FHRS, Jess Oren, MD and Angela Naperkowski, RN. Geisinger Heart Institute, Wilkes-Barre, PA, Indiana University, Indianapolis, IN, Geisinger Heart Institute, Danville, PA; Heart Rhythm Society (HRS) Scientific Sessions 2017, C-AB26-06, May 12, 2017

Permanent His bundle pacing: Electrophysiological and echocardiographic observations from long-term follow-up; Pugazhendhi Vijayaraman MD, FHRS, Gopi Dandamudi MD, FHRS, Daniel Lustgarten MD, FHRS, Kenneth A Ellenbogen MD, FHRS; Pacing and Clinical Electrophysiology, Volume 40, Issue 7, July 2017, Pages 883–891

Pacing-induced cardiomyopathy in patients with right ventricular stimulation for >15 years; Henryk Dreger, Katja Maethner, Hansjürgen Bondke, Gert Baumann, Christoph Melzer; EP Europace, Volume 14, Issue 2, 1 February 2012, Pages 238–242

Permanent His-bundle Pacing is Feasible, Safe, and Superior to Right Ventricular Pacing in Routine Clinical Practice; Parikshit S. Sharma, MD, MPH; Gopi Dandamudi, MD, FHRS; Angela Naperkowski, RN, FHRS, CCDS, CEPS (Geisinger Wyoming Valley Medical Center, Wilkes Barre, Pennsylvania); Jess W.Oren, MD; Randle H.Storm, MD, FHRS (Geisinger Medical Center, Danville, Pennsylvania); Kenneth A. Ellenbogen, MD, FHRS (Virginia Commonwealth University Medical Center, Richmond, Virginia); Pugazhendhi Vijayaraman, MD, FHRS (Geisinger Wyoming Valley Medical Center, Wilkes Barre, Pennsylvania); Heart Rhythm, Vol. 12, No 2, February 2015; prior, Heart Rhythm Society, Scientific Sessions, 2014

Incidence and predictors of right ventricular pacing-induced cardiomyopathy in patients with complete atrioventricular block and preserved left ventricular systolic function; Kiehl, E. MD, Makki, T. MD, Kumar, R. MD, Divya, G. MD, Kwon, D. MD, Richard, J. MD, FHRS, Kanj, M. MD, FHRS, Wazni, O. MD, FHRS, Saliba, W, MD, FHRS, Varma, N. MD, FHRS, Wilkoff, B. MD, FHRS, Caltillon, D. MD, FHRS; Heart Rhythm; Vol 13, Is 12, Dec., 2016, p. 2272–2278

Incidence and Predictors of Heart Failure Hospitalization and Death in Permanent Pacemaker Patients: a Single-Center Experience over Medium-term Follow-up; Mazza, Bendini, Leggio, Riva, Ciardiello, Valsecchi, De Cristofaro, and Giordano; Europace (2013) 15. 1267-1272

Tricuspid Valve Dysfunction Following Pacemaker or Cardioverter-Defibrillator Implantation; James D. Chang, Warren J. Manning, Elisa Ebrille, Peter J. Zimetbaum; Journal of the American College of Cardiology May 09, 2017, 69 (18) 2331-2341; DOI: 10.1016/j.jacc.2017.02.055

The Continued Search for Physiological Pacing Where Are We Now?; Pugazhendhi Vijayaraman, Pierre Bordachar, Kenneth A. Ellenbogen; Journal of the American College of Cardiology; Volume 69, Issue 25, 27 June 2017, Pages, 3099-3114

Incidence and Predictors of Right Ventricular Pacing-induced Cardiomyopathy; Khurshid, S. MD, Epstein, A. MD, FHRS, Verdino, R. MD, Lin, D. MD, FHRS, Goldberg, L. MD, Marchlinski, F. MD, FHRS, Frankel, D. MD, FHRS; Heart Rhythm, Vol 11, Is 9, Sept., 2014, p. 1619-1625

Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacing; Thambo JB, Bordachar P, Garrigue S, Lafitte S, Sanders P, Reuter S, Girardot R, Crepin D, Reant P, Roudaut R, Jaïs P, Haïssaguerre M, Clementy J, Jimenez M; Circulation, 2004 Dec 21, 110(25):3766-72

Dual-Chamber Pacing or Ventricular Backup Pacing in Patients With an Implantable Defibrillator, The Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial; Wilkoff, B. MD, Cleveland Clinic Foundation; JAMA, Dec. 25, 2002, Vol. 288, No. 24:3115-3123

Adverse Effect of Ventricular Pacing on Heart Failure and Atrial Fibrillation Among Patients With Normal Baseline QRS Duration in a Clinical Trial of Pacemaker Therapy for Sinus Node Dysfunction; Sweeney, Michael O. MD, Hellkamp, Anne S. MS; Ellenbogen, Kenneth A. MD; Greenspon, Arnold J. MD; Freedman, Roger A. MD; Lee, Kerry L. PhD; Lamas, Gervasio A. MD; for the Mode Selection Trial (MOST) Investigators; Circulation, 2003:107:2932-2937

Physiology of Cardiac Pacing in Children: The Importance of the Ventricular Pacing Site; Vanagt, Ward Y.; Prinzen, Fritz W.; Delhass, Tammo; Pacing & Clinical Electrophysiology. Jan 2008 Supplement 1, Vol. 31, pS24-S27, 1p, 1 bw; DOI: 10.1111/j.1540-8159.2008.00950.x;(AN 28542760)

His or para-His Pacing Preserves Left Ventricular Function in AV Block: a Double-blind, Randomized, Crossover Study; Kronborg, M., Mortensen, P., Poulsen, S.,Gerdes, J., Jensen, H., Nielsen, J.; Europace (2014)

What are the harmful effects of conventional pacing, on heart muscle structure and function?

Abnormal Conduction-Induced Cardiomyopathy: JACC Review Topic of the Week; Jose F. Huizar, Karoly Kaszala, Alex Tan, Jayanthi Koneru, Pranav Mankad, Jordana Kron, and Kenneth A. Ellenbogen; J Am Coll Cardiol. 2023 Mar, 81 (12) 1192–1200

Effects of haemodynamically atrio-ventricular optimized His-pacing on heart failure symptoms and exercise capacity; Zachary I Whinnett PhD, Matthew J Shun-Shin PhD, Mark Tanner MD, Paul Foley PhD, Badri Chandrasekaran MD, Philip Moore PhD, Shaumik Adhya PhD …; European Journal of Heart Failure, 20 November 2022, https://doi.org/10.1002/ejhf.2736

Impact of physiological pacing on functional mitral regurgitation in systolic dysfunction: Initial echocardiographic remodeling findings after His bundle pacing; Gaurav A. Upadhyay, MD, FACC, FHRS. Michael Henry, MD, Davide Genovese, MD, Parth Desai, MD. Jonathan Lattell, MD, Hannah Wey, MD, Stephanie A. Besser, MSAS, Zaid Aziz, MD, Andrew D. Beaser, MD, Cevher Ozcan, MD, Hemal M. Nayak, MD, FACC, FHRS, Roberto M. Lang, MD, FASE, FESC, Roderick Tung, MD, FACC, FHRS; Heart Rhythm, VOLUME 2, ISSUE 5, P446-454, OCTOBER 01, 2021, DOI:https://doi.org/10.1016/j.hroo.2021.07.007, Published: July 25, 2021

Occurrence of persistent atrial fibrillation during pacing for sinus node disease: The influence of His bundle pacing versus managed ventricular pacing; Gianni Pastore, Lina Marcantoni, Daniela Lanza, Massimiliano Maines, Franco Noventa, Giorgio Corbucci, Gianluca Rigatelli, Enrico Baracca, Loris Roncon, Francesco Zanon; J Cardiovasc Electrophysiol, 2021 Jan;32(1):110-116. doi: 10.1111/jce.14810. Epub 2020 Nov 18, PMID: 33179400 DOI: 10.1111/jce.14810

Development of New-Onset or Progressive Atrial Fibrillation in Patients With Permanent HIS Bundle Pacing vs Right Ventricular Pacing; Venkatesh Ravi, Dominik Beer, Grzegorz M. Pietrasik, Jillian L. Hanifin, Sara Ooms, Muhammad Talha Ayub, Timothy Larsen, Henry D. Huang, Kousik Krishnan, Richard G. Trohman, Pugazhendhi Vijayaraman, and Parikshit S. Sharma; Journal of the American Heart Association. 2020;9, https://doi.org/10.1161/JAHA.120.018478

His-bundle pacing: promise for the future; Pugazhendhi Vijayaraman Sergio Richter EP; Europace, Volume 21, Issue 5, May 2019, Pages 686–687, https://doi.org/10.1093/europace/euy318

Tricuspid Valve Dysfunction Following Pacemaker or Cardioverter-Defibrillator Implantation; James D. Chang, Warren J. Manning, Elisa Ebrille and Peter J. Zimetbaum; Cardiovascular Division, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts, Department of Radiology, Harvard Medical School, Boston, Massachusetts; Journal of the American College of Cardiology, Vol 69, Issue 18, May 2017

Adverse effects of atrioventricular synchronous right ventricular pacing on left ventricular sympathetic activity, efficiency, and hemodynamic status; Abdul Al-Hesayen and John D. Parker; Department of Medicine, Division of Cardiology, Mount Sinai and University, Health Network Hospitals, University of Toronto, Toronto, Ontario, Canada; Am J Physiol Heart Circ Physiol 291: H2377–H2379, 2006

Strategically Targeting Calcium: Altering activation sequence to reverse remodel the failing ventricle; Lance D. Wilson, MD, Isabelle Deschenes, PhD; Heart Rhythm, DOI: https://doi.org/10.1016/j.hrthm.2018.04.023

Deleterious Effects of Right Ventricular Pacing; Lindsay, Bruce D., M.D; The New England Journal of Medicine, November 15, 2009, 10.1056/NEJMe0909522

Myofibrillar disarray produced in normal hearts by chronic electrical pacing; Gerald E Adomian, PhD., James Beazell, M.S, UCLA School of Medicine Los Angeles, Calif.; American Heart Journal, July 1986, Vol. 112, Issue 1, Pages 79–83

Right ventricular pacing impairs endothelial function in man; AM Choy, HHM Su, DHJ Elder, A Noman, M Pauriah, AD Struthers, CC Lang; Centre for Cardiovascular and Lung Biology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK. a.choy@dundee.ac.uk; Europace, 2011 Jun,13(6):853-8. doi: 10.1093/europace/eur028. Epub 2011 Feb 22.

The Risk of Atrial Fibrillation during Right Ventricular Pacing; Pastore, G.,Zanon, F., Baracca, E., Aggio, S., Corbucci, G., Baretto, G., Roncon, L., Noventa, F., Barold, SS.; Europace, 2016 March, 18(3): 353-8

Adverse Effects of Long-Term Right Ventricular Apical Pacing and Identification of Patients at Risk of Atrial Fibrillation and Heart Failure; De Sisti, Antonio M.D., Marquez, Manlio, M.D., Tonet, Joelci, M.D., Bonny, Aim, M.D., Frank, Robert, M.D., Hidden-Lucet, Francoise, M.D.; PACE, August 2012, Vol. 35, Issue 8, pp 1035-1043

His Bundle Pacing: Techniques and Outcomes; Kronborg MB¹, Nielsen JC²; ¹Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus, Denmark, Mads.Brix.Kronborg@ki.au.dk, ²Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus, Denmark; Curr Cardiol Rep. 2016 Jul;18(8):76. doi: 10.1007/s11886-016-0748-3

Right Ventricular Apical Pacing-induced Left Ventricular Dyssynchrony is Associated with a Subsequent Decline in Ejection Fraction; Ahmed, M, MD, Gorcsan, J, MD, Marek, J, MD, Ryo, K, MD, Haugaa, K, MD, Ludwig, D, ScB, Schwartzman, D, MD, FHRS; Heart Rhythm, April,2014, Vol. 11, Is. 4:602-608

Direct His Bundle Pacing Preserves Coronary Perfusion Compared With Right Ventricular Apical Pacing: a Prospective, Cross-over Mid-term Study; Zanon F., Bacchiega E., Rampin L., Aggio S., Baracca E., Pastore G., Marotta T., Corbucci G., Roncon L., Rubello D., Prinzen F.W.; Europace; 2008 May;10(5):580-7. Epub 2008 Apr 11

Redistribution of Myocardial Fiber Strain and Blood Flow by Asynchronous Activation; Prinzen, F., Augustijn, C., Atrs, T., Allessie, M., & Reneman, R.; American Physiological Society, 1990, 0363-6135/90

Asymmetric Thickness of the Left Ventricular Wall Resulting from Asynchronous Electric Activation: A Study in Dogs with Ventricular Pacing and in Patients with Left Bundle Branch Block; Prinzen, F. PhD, Cheriex, E. MD, Delhaas, T. MD, PhD, van Oosterhout, M. MD, Arts, T. PhD, Wellena, H. MD, PhD, & Reneman, R. MD, PhD; Maastricht, The Netherlands, American Heart Journal, Nov. 1995, Vol. 130, No. 5

Permanent His-Bundle Pacing Maintains Long-Term Ventricular Synchrony and Left Ventricular Performance, Unlike Conventional Right Ventricular Apical Pacing; Catanzari, D., Maines, M., Manical, A., Angheben, C., Varbaro, A., Vergara, G., Division of Cardiology, Santa Maria del Carmine Hospital, Rovereto (TN), Italy, Medtronic Italia,Sesto S.G. (MI), Italy; Europace (2013) 15 (4) : 546-553

Hisian area and Right Ventricular Apical Pacing Differently Affected Left Atrial Function: an Intra-patient Evaluation; Pastore, Aggio, Baracci, Fraccaro, Picariello, Roncon, Corbucci, Noventa and Zanon; Europace (2013)

His-bundle Stimulation and Alternative RV Stimulation Sites; Fröhlig G, Kindermann M.; Herzschrittmacherther Elektrophysiol, 2008 Mar; 19(1):30-40, Review, German

Left Ventricular Performance during para-His Pacing in Patients with High-degree Atrioventricular Block: an acute study; Kronborg, M., Poulsen, S., Mortensen,P., Nielsen, J.; Europace,2012 June 14; 14(6):841-6. Epub 2011 Dec 14

Altered Cardiac Histology Following Apical Right Ventricular Pacing in Patients with Congenital Atrioventricular Block; Peter P. Karpawich, Raha Rabah, Joel E. Haas; Section of Cardiology, Children’s Hospital of Michigan, Wayne State University School of Medicine; Pacing Clin Electrophysiol. 1999 Sep;22(9):1372-7

Developmental sequelae of fixed-rate ventricular pacing in the immature canine heart: An electrophysiologic, hemodynamic, and histopathologic evaluation; Peter P.Karpawich, MD, Cheryl D.Justice, Dianne L.Cavitt, CCVT, Chung-HoChang, MD, Department of Pediatrics, Children’s Hospital of Michigan, Wayne State University School of Medicine; American Heart Journal, Vol. 119, Issue 5, May 1990, Pages 1077-1083

His / Purkinje system pacing matures to include left bundle branch pacing

His-Synchronous RV Pacing – Properly interpreting a Common Manoeuvre; Cardiac Physiology; Posted July 21, 2024

Outcomes with Physiologic His Bundle Pacing in Patients with Narrow QRS Complex; Rehan Mahmud, M.D., Jenna Lee, B.Sc., Ayush Mohan, M.D., Sharon Hakes, RN, Fahimeh Talaei, M.D., Eduardo Back Sternick, M.D., Ph.D, F.H.R.S, Matt Lee, M.D., Brittany Phillips, B.Sc.; DOI:https://doi.org/10.1016/j.hrthm.2024.06.027

Effect of left bundle branch pacing on right ventricular function: A 3-dimensional echocardiography study; Fangyan Tian, MD, Haobo Weng, MD, Ao Liu, MD, Wen Liu, MD, Bei Zhang, MD, Yanan Wang, MD, Yufei Cheng, MD, Shan Cheng, MD, Zibire Fulati, MD, Nianwei Zhou, MD, Dehong Kong, MD, Cuizhen Pan, MD, Yangang Su, MD, FHRS, Nuo Xu, MD, Haiyan Chen, MD, Xianhong Shu, MD, PhD; Dec 23, 2023, DOI:https://doi.org/10.1016/j.hrthm.2023.12.012

Bipolar anodal septal pacing with direct LBB capture preserves physiological ventricular activation better than unipolar left bundle branch pacing; Karol Curila, Pavel Jurak, Frits Prinzen, Marek Jastrzebski, Petr Waldauf, Josef Halamek, Marketa Tothova, Lucie Znojilova, Radovan Smisek, Jakub Kach, Lukas Poviser, Hana Linkova, Filip Plesinger, Pawel Moskal, Ivo Viscor, Vlastimil Vondra, Pavel Leinveber, Pavel Osmancik; Frontiers in Cardiovascular Medicine, 22 March 2023, doi: https://doi.org/10.1101/2023.01.09.23284263

Comparisons of electrophysiological characteristics, pacing parameters and mid- to long-term effects in right ventricular septal pacing, right ventricular apical pacing and left bundle branch area pacing; Wenhua Li, Yu Ding, Chao Gong, Genqing Zhou, Xiaofeng Lu, Yong Wei, Shi Peng, Lidong Cai, Tianyou Yuan, Fangfang Li, Shaowen Liu, Songwen Chen; BMC Cardiovascular Disorders, 19 September 2022

Left bundle branch area pacing in patients with atrioventricular conduction disease: A prospective multicenter study; Alexandre Raymond-Paquin MD, Atul Verma MD, Jeffrey Kolominsky MD, Paula Sanchez-Somonte MD, Enes Elvin Gul MD, Ajay Pillai MD, Jordana Kron MD, Richard Shepard MD, Gautham Kalahasty MD, Bernice T sang MD, Yaariv Khaykin MD, Alfredo Pantano MD, Jayanthi N. Koneru MBBS, Kenneth A. Ellenbogen MD, FHRS; Heart Rhythm, Sep. 01, 2022, Vol. 19, ISSUE 9, P1484-1490

Left Bundle Branch Area Pacing In Patients with Heart Failure and Right Bundle Branch Block: Results From International LBBAP Collaborative-Study Group; Pugazhendhi Vijayaraman, MD, FHRS, Oscar Cano, MD, Shunmuga Sundaram Ponnusamy, MBBS, MD, CEPS-A, Manuel Molina-Lerma, MD, Joseph Y.S. Chan, MBBS, Santosh K. Padala, MBBS, Parikshit S. Sharma, MD, MPH, Zachary I. Whinnett, BMBS, PhD, Bengt Herweg, MD, FHRS, Gaurav A. Upadhyay, MD, FHRS, Faiz A. Subzposh, MD, Neil R. Patel, MD, MPH, Dominik A. Beer, DO, Agnieszka Bednarek, MD, PhD, Grzegorz Kielbasa, MD, Roderick Tung, MD, FHRS, Kenneth A. Ellenbogen, MD, FHRS, Marek Jastrzebski, MD, PhD; Heart Rhyrhm, May 13, 2022, DOI:https://doi.org/10.1016/j.hroo.2022.05.004

Clinical outcomes of conduction system pacing compared to biventricular pacing in patients requiring cardiac resynchronization therapy; Pugazhendhi Vijayaraman, MD, FHRS, Dipen Zalavadia, MD, Abdul Haseeb, MD, Cicely Dye, MD, Nidhi Madan, MD, Jamario Renaldo Skeete, MD, Sharath C. Vipparthy, MD, Wilson Young, MD, PhD, Venkatesh Ravi, MD, Clement Rajakumar, BS, Parash Pokharel, MD, Timothy Larsen, DO, Henry D. Huang, MD, FHRS, Randle H. Storm, MD, FHRS, Jess W. Oren, MD, Syeda Atiqa Batul, MBBS, MD, Richard G. Trohman, BS, MBA, MD, FHRS, Faiz A. Subzposh, MD, Parikshit S. Sharma, MD, MPH, FHRS; Heart Rhythm, April 29, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.04.023

Tricuspid regurgitation outcomes in left bundle branch area pacing and comparison with right ventricular septal pacing; Xiaofei Li, MD, Haojie Zhu, MD, Xiaohan Fan, MD, PhD, Hao Wang, MD, Zhimin Liu, MD, Yan Yao, MD, PhD; Heart Rhythm, March 09, 2022, DOI: https://doi.org/10.1016/j.hrthm.2022.03.005

Response of functional mitral regurgitation in nonischemic cardiomyopathy to left bundle branch pacing; Shunmuga Sundaram Ponnusamy, MD, DM, CEPS, Thabish Syed, MBBS, DNB, Pugazhendhi Vijayaraman, MD, FHRS; Heart Rhythm, January 20, 2022, DOI: https://doi.org/10.1016/j.hrthm.2022.01.019

Pursue physiological pacing therapy: A better understanding of left bundle branch pacing and left ventricular septal myocardial pacing; Weijian Huang, MD, FHRS, Xiaohong Zhou, MD, Kenneth A. Ellenbogen, MD, FHRS; Heart Rhythm Journal, May 12, 2021, DOI:https://doi.org/10.1016/j.hrthm.2021.05.013

Complications with left bundle branch area pacing; Haran Burri, MD, FEHRA; Heart Rhythm, January 31, 2022, DOI: https://doi.org/10.1016/j.hrthm.2022.01.032

Clinical outcomes of left bundle branch area pacing compared to right ventricular pacing: Results from the Geisinger-Rush Conduction System Pacing Registry; Parikshit S Sharma, Neil R Patel, Venkatesh Ravi, Dipen V Zalavadia, Sujitraj Dommaraju, Varun Garg, Timothy R Larsen, Angela M Naperkowski, Jeremiah Wasserlauf, Kousik Krishnan, Wilson Young, Parash Pokharel, Jess W Oren, Randle H Storm, Richard G Trohman, Henry D Huang, Faiz A Subzposh, Pugazhendhi Vijayaraman; Heart Rhythm, VOLUME 19, ISSUE 1, P3-11, JANUARY 01, 2022

Is Left Bundle Area Pacing the Future of Pacing for Bradycardia? Chau N. Vo, MD, Michael R. Gold, MD, PhD, FHRS; October 05, 2021DOI: https://doi.org/10.1016/j.hrthm.2021.09.039

Left bundle branch pacing compared to left ventricular septal myocardial pacing increases interventricular dyssynchrony but accelerates left ventricular lateral wall depolarization; Karol Curila, MD, PhD, MSc, Pavel Jurak, MSc, PhD, Marek Jastrzebski, MD, PhD, Frits Prinzen, PhD, Petr Waldauf, MD, PhD, Josef Halamek, MSc, PhD, Kevin Vernooy, MD, PhD, Radovan Smisek, MSc, Jakub Karch, MSc, Filip Plesinger, MSc, PhD, Pawel Moskal, MD, PhD, Marketa Susankova, MSc, Lucie Znojilova, MSc, Luuk Heckman, MD, Ivo Viscor, MSc, PhD, Vlastimil Vondra, PhD, Pavel Leinveber, MSc, Pavel Osmancik, MD, PhD; Heart Rhythm Journal, Vol 18, Issue 8, P1281-1289, August 01, 2021

Left bundle branch-optimized cardiac resynchronization therapy (LOT-CRT): results from an international LBBAP collaborative study group; Marek Jastrzębski, MD, PhD, Paweł Moskal, MD, PhD, Wim Huybrechts, MD, Karol Curila, MD, PhD, Praveen Sreekumar, MBBS, MD, DM, Leonard M. Rademakers, MD, PhD, Shunmuga Sundaram Ponnusamy, MBBS, MD, CEPS-A, Bengt Herweg, MD, FHRS, Parikshit S. Sharma, MD, MPH, FACC, FHRS, Agnieszka Bednarek, MD, PhD, Marek Rajzer, MD, PhD, Pugazhendhi Vijayaraman, MD, FHRS; Heart Rhythm Journal, July 30, 2021DOI:https://doi.org/10.1016/j.hrthm.2021.07.057

Evaluation of the Criteria to Distinguish Left Bundle Branch Pacing from Left Ventricular Septal Pacing; Shengjie Wu MD, XueyingChenMD, PhD, Songjie Wang, MD, Lei Xu, MD, Fangyi Xiao MD, Zhouqing Huang MD, Rujie Zheng MD, Limeng Jiang, MD, Pugazhendhi Vijayaraman MD, Parikshit S. Sharma, MD, Lan Su, MD, Weijian Huang, MD; JACC: Clinical Electrophysiology, Available online 28 April 2021

Three-dimensional guided selective right ventricular septal pacing preserves ventricular systolic function and synchrony in pediatric patients; Massimo Stefano Silvetti, Vincenzo Pazzano, Irma Battipaglia, Fabio Anselmo Saputo, Chiara Mizzon, Fabrizio Gimigliano, Antonio Ammirati, Lucilla Ravà, Fabrizio Drago; Heart Rhythm, 2021 Mar,18(3):434-442, (doi: 10.1016/j.hrthm.2020.12.004), Epub 2020 Dec 8

Procedure-Related Complications of Left Bundle Branch Pacing: A Single-Center Experience; Xueying Chen, Lanfang Wei, Jin Bai, Wei Wang, Shengmei Qin, Jingfeng Wang, Yixiu Liang, Yangang Su and Junbo Ge; Cardiovasc. Med., 24 March 2021, https://doi.org/10.3389/fcvm.2021.645947

The Relationship of Paced Left Bundle Branch Pacing Morphology with Anatomic Location and Physiologic Outcomes; Jinxuan Lin, MD, Qingyun Hu, MD, Keping Chen, MD, PhD, FHRS, Feng Chen, MD, PhD, Michael R. Gold, MD, PhD, FHRS, Shu Zhang, MD, PhD, FHRS; Heart Rhythm Society, March 26, 2021, DOI:https://doi.org/10.1016/j.hrthm.2021.03.034

Comparing Ventricular Synchrony in Left Bundle Branch and Left Ventricular Septal Pacing in Pacemaker Patients; Luuk I. B. Heckman, Justin G. L. M. Luermans, Karol Curila, Antonius M. W. Van Stipdonk, Sjoerd Westra, Radovan Smisek, Frits W. Prinzen and Kevin Vernooy; Journal of Clinical Medicine, 16 Feb 2021, vol 10(4) DOI: 10.3390/jcm10040822

Long-Term Safety and Feasibility of Left Bundle Branch Pacing; Lan Su, Songjie Wang, Shengjie Wu, Lei Xu, Zhouqing Huang, Xiao Chen, Rujie Zheng, Limeng Jiang, Kenneth A. Ellenbogen, Zachary I. Whinnett, and Weijian Huang; Circulation: Arrhythmia and Electrophysiology, 9 Jan 2021. https://doi.org/10.1161/CIRCEP.120.009261

LBB Area Pacing for Cardiac Resynchronization Therapy; Óscar Cano, MD; Pugazhendhi Vijayaraman, MD, FACC; JACC, Jan 25, 2021

A deeper look into conduction system pacing: From the bench to the bedside; Kenneth A. Ellenbogen, MD, FHRS, Santosh K. Padala, MD; Heart Rhythm Journal, January 18, 2021, DOI:https://doi.org/10.1016/j.hrthm.2021.01.015

His-bundle and left bundle pacing with optimized atrioventricular delay achieve superior electrical synchrony over endocardial and epicardial pacing in left bundle branch block patients; Marina Strocchi, MSc, Angela W.C. Lee, PhD, Aurel Neic, PhD, Julien Bouyssier, PhD, Karli Gillette, MSc, Gernot Plank, PhD, Mark K. Elliott, MBBS, Justin Gould, PhD, Jonathan M. Behar, MBBS, Baldeep Sidhu, MBBS, Vishal Mehta, MBBS, Martin J. Bishop, PhD, Edward J. Vigmond, PhD, Christopher A. Rinaldi, MBBS, MD, FHRS, Steven A. Niederer, PhD; CLINICAL HEART FAILURE, VOLUME 17, ISSUE 11, P1922-1929, NOVEMBER 01, 2020

Initial Experience, Safety, and Feasibility of Left Bundle Branch Area Pacing, Santosh K. Padal; Vivak M. Master, Maria Terricabras, Andrea Chiocchini, Aatish Garg, Jordana Kron, Richard Shepard, Gautham Kalahasty, Zahara Azizi, Bernice Tsang, Yaariv Khaykin, Alfredo Pantano, Jayanthi N. Koneru, Kenneth A. Ellenbogen and Atul Verma; JACC: Clinical Electrophysiology, DOI: 10.1016/j.jacep.2020.07.004, September 2020

Comparison of Left Bundle Branch and His Bundle Pacing in Bradycardia Patients; Wei Hua, Xiaohan Fan, Xiaofei Li, Hongxia Niu, Min Gu, Xiaohui Ning, Yiran Hu, Michael R. Gold and Shu Zhang; JACC: Clinical Electrophysiology, August 2020, DOI: 10.1016/j.jacep.2020.05.008

Left bundle branch pacing is the best approach to physiological pacing; Santosh K. Padala, MD, Kenneth A. Ellenbogen, MD, FHRS; Heart Rhythm Society, VOLUME 1, ISSUE 1, P59-67, APRIL 01, 2020

Left Bundle Branch Pacing: JACC Review Topic of the Week; Shu Zhang, Xiaohong Zhou, and Michael R. Gold; J Am Coll Cardiol. 2019 Dec, 74 (24) 3039–3049

What about His / Left Bundle Branch pacing for cardiac resynchronization therapy (CRT)

Conduction System Pacing Compared To Biventricular Pacing For Cardiac Resynchronization Therapy In Patients With Heart Failure and Mildly Reduced Left Ventricular Ejection Fraction: Results From International Collaborative LBBAP Study (I-CLAS) Group; Pugazhendhi Vijayaraman, MD, pvijayaraman1@geisinger.edu, Francesco Zanon, MD, Shunmuga Sundaram Ponnusamy, MD, Bengt Herweg, MD, Parikshit Sharma, MD, MPH, Manuel Molina-Lerma, MD6, Marek Jastrzębski, MD, PhD, Zachary Whinnett, MD, PhD, Kevin Vernooy, MD, PhD, Rajeev K. Pathak, MBBS, PhD, Roderick Tung, MD, Gaurav Upadhyay, MD, Karol Curila, MD, PhD, Dipen Zalavadia, MD, Nischay Shah, MD, Lina Marcantoni, MD, Mohamed Gad, MD, Ramez Morcos, MD, Pawel Moskal, MD, Akriti Naraen, MD, Mishal Mumtaz, MD, Jamario R. Skeete, MD, Praneet S. Katrapati, MD, Jeffrey Kolominsky, MD, Johan van koll, MD, Mihail G. Chelu, MD, PhD, Kenneth A. Ellenbogen, MD, Oscar Cano, MD, PhD; Heart Rhythm, September 26, 2024

LVSP and LBBP Result in Similar or Improved LV Synchrony and Hemodynamics Compared to BVP; Karol Curila MD, PhD, MS, Lukas Poviser MS, Petr Stros MD, Pavel Jurak MSc, PhD, Zachary Whinnett MD, PhD, Marek Jastrzebski MD, PhD, Petr Waldauf MD, PhD, Radovan Smisek MS, Ivo Viscor MS, Marek Hozman MD, Pavel Osmancik MD, PhD, Lukas Kryze MD, Josef Kautzner MD, PhD; JACC: Clinical Electrophysiology, Volume 10, Issue 7, Part 2, July 2024, Pages 1722-1732

Ineffective Cardiac Resynchronization Pacing is Associated with Poor Outcomes in a Nationwide Cohort Analysis; Shelief Y. Robbins-Juarez, MD, Suneet Mittal, MD, FHRS, Chris Plummer, PhD, FRCP, Jodi L. Koehler, MS, Robert W. Stadler, PhD, Subham Ghosh, PhD, Ruth N. Klepfer, PhD, Jonathan P. Piccini, MD, MHS, FHRS, July 17, 2024, DOI:https://doi.org/10.1016/j.hrthm.2024.06.064

Outcomes of Upgrading to LBBP in CRT Nonresponders: A Prospective, Multicenter, Nonrandomized, Case-Control Study; Xueying Chen MD, Qinchun Jin MD, Zhaohui Qiu MD, Caizhen Qian MD, Yixiu Liang MD, Jingfeng Wang MD, Shengmei Qin MD, Jin Bai MD, Wei Wang MD, Haiyan Chen MD, Yingxue Dong MD, Weijian Huang MD, Yangang Su MD; JACC: Clinical Electrophysiology, Vol 10, Issue 1, January 2024, Pages 108-120

A step forward towards conduction system pacing–based cardiac resynchronization therapy, albeit a small one; Marek Jastrzębski, MD, PhD, Pugazhendhi Vijayaraman, MD; Published:February 15, 2024DOI:https://doi.org/10.1016/j.hrthm.2024.02.025

Efficacy of Left Bundle Branch Area Pacing Versus Biventricular Pacing in Cardiac Resynchronization Therapy Patients: Select Site – Cohort Study; Jenish P. Shroff, DM, Deep Chandh Raja, DM, Lukah Q. Tuan, BSc, Walter P. Abhayaratna, MBBS, PhD, Prashanthan Sanders, MBBS, PhD, FHRS, Rajeev K. Pathak, MBBS, PhD, FHRS; Published:February 15, 2024DOI:https://doi.org/10.1016/j.hrthm.2024.02.024

His-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy vs Biventricular Pacing: HOT-CRT Clinical Trial; Pugazhendhi Vijayaraman MD, Parash Pokharel MD, Faiz A. Subzposh MD, Jess W. Oren MD, Randle H. Storm MD, Syeda A. Batul MD, Dominik A. Beer DO, Grace Hughes BS, MPH, Gabriella Leri BS, Marilee Manganiello MSN, CRNP, Jennifer L. Jastremsky MHA, RCDS, Kaitlyn Mroczka BS, RCDS, Alicia M. Johns PhD, Vernon Mascarenhas MD; Volume 9, Issue 12, December 2023, December 2023, Pages 2628-2638

Sex-specific Outcomes of LBBAP versus Biventricular pacing: Results from the International Collaborative LBBAP Study (I-CLAS); Faiz A. Subzposh, Parikshit S. Sharma, Óscar Cano, Shunmuga Sundaram Ponnusamy, Bengt Herweg, Francesco Zanon, Marek Jastrzebski, Jiangang Zou, Mihail G. Chelu, Kevin Vernooy, Zachary I. Whinnett, Girish M. Nair, Manuel Molina-Lerma, Karol Curila, Kenneth A. Ellenbogen, and Pugazhendhi Vijayaraman; J Am Coll Cardiol EP. Sep 02, 2023. Epublished DOI: 10.1016/j.jacep.2023.08.026

Electrical Resynchronization and Clinical Outcomes During Long-Term Follow-Up in Intraventricular Conduction Delay Patients Applied Left Bundle Branch Pacing-Optimized Cardiac Resynchronization Therapy; Xueying Chen, Xiao Li, Yingnan Bai, Jingfeng Wang, Shengmei Qin, Jin Bai, Wei Wang, Yixiu Liang, Haiyan Chen, Yangang Su and Junbo Ge; Originally published14 Aug 2023https://doi.org/10.1161/CIRCEP.122.011761Circulation: Arrhythmia and Electrophysiology. 2023;0:e011761

Left Bundle Branch Area Pacing Versus Biventricular Pacing as Initial Strategy for Cardiac Resynchronization; Juan Carlos Diaz, William H. Sauer, Mauricio Duque, Bruce A. Koplan, Eric D. Braunstein, Jorge Eduardo Marín, Julian Aristizabal, Cesar Daniel Niño, Oriana Bastidas, Juan Manuel Martinez, Carolina Hoyos, Carlos D. Matos, Nestor Lopez-Cabanillas, Nathaniel A. Steiger, Sunil Kapur, Thomas M. Tadros, David T. Martin, Paul C. Zei, Usha B. Tedrow, and Jorge E. Romero; J Am Coll Cardiol EP. May 21, 2023. Epublished DOI: 10.1016/j.jacep.2023.04.015

LB-456087-3 HIS-PURKINJE CONDUCTION SYSTEM PACING OPTIMIZED TRIAL OF CARDIAC RESYNCHRONIZATION THERAPY VERSUS BIVENTRICULAR PACING: A RANDOMIZED CONTROLLED CLINICAL TRIAL (HOTCRT); Pugazhendhi Vijayaraman, Parash Pokharel, Faiz A. Subzposh, Jess W. Oren, Randle H. Storm, Syeda Atiqa Batul, Dominik A. Beer, Gabrielle Leri, Marilee Manganiello, Grace Hughes, Alicia Johns, Vernon Mascarenhas; Heart Rhythm, May 16, 2023, DOI:https://doi.org/10.1016/j.hrthm.2023.04.039

LB-456088-1 LEFT BUNDLE BRANCH AREA PACING COMPARED TO BIVENTRICULAR PACING FOR CARDIAC RESYNCHRONIZATION THERAPY: RESULTS FROM INTERNATIONAL LBBAP COLLABORATIVE STUDY GROUP; Pugazhendhi Vijayaraman, Parikshit S. Sharma, Óscar Cano, Shunmuga Sundaram, Ponnusamy, Bengt Herweg, Francesco Zanon, Marek Jastrzebski. Jiangang Zou, Mihail G. Chelu, Kevin Vernooy, Zachary I. Whinnett, Girish M. Nair, Manuel Molina-Lerma, Karol Curila, Dipen Zalavadia, Abdul Haseeb, Cicely Dye, Sharath C. Vipparthy, Ryan Brunetti, Pawel Moskal, Jeffrey Kolominsky, Alexandra Ross, Antonius van Stipdonk, Jerin George, Yusuf K. Qadeer, Mishal Mumtaz, Syeda A. Zahra, Mehrdad Golian, Lina Marcantoni, Faiz A. Subzposh, Kenneth A. Ellenbogen; Heart Rhythm, May 16, 2023, DOI:https://doi.org/10.1016/j.hrthm.2023.04.044

Left bundle branch area pacing reduces epicardial dispersion of repolarization compared with biventricular cardiac resynchronization therapy; Mark K. Elliott, MBBS, PhD, Marina Strocchi, PhD, Benjamin J. Sieniewicz, MBChB, PhD, Martin J. Bishop, PhD, Steven Niederer, PhD, Christopher A. Rinaldi, MD, FHRS; Published:July 27, 2023DOI:https://doi.org/10.1016/j.hrthm.2023.07.065

Improved outcomes of conduction system pacing in heart failure with reduced ejection fraction: A systematic review and meta-analysis; Julian Gin, BSc, MD, Chee Loong Chow, MBBS, Alex Voskoboinik, MBBS (Hons), PhD, Han S. Lim, MBBS, PhD, Jonathan M. Kalman, MBBS, PhD, Geoffrey R. Wong, MBBS, PhD; Heart Rhythm, May 10, 2023 DOI:https://doi.org/10.1016/j.hrthm.2023.05.010

Outcomes of conduction system pacing for cardiac resynchronization therapy in patients with heart failure: A multicenter experience; Fatima M. Ezzeddine, MD, Serafim M. Pistiolis, MD, Margarida Pujol-Lopez, MD, Michael Lavelle, MD, Elaine Y. Wan, MD, FHRS, Kristen K. Patton, MD, FHRS, Melissa Robinson, MD, FHRS, Adi Lador, MD, Kamala Tamirisa, MD, FHRS, Saima Karim, DO, FHRS, Cecilia Linde, MD, Ratika Parkash, MD, MSc, FHRS, Ulrika Birgersdotter-Green, MD, FHRS, Andrea M. Russo, MD, FHRS, Mina Chung, MD, FHRS, Yong-Mei Cha, MD, FHRS; Heart Rhythm, February 24, 2023, DOI:https://doi.org/10.1016/j.hrthm.2023.02.018

Resynchronization effects and clinical outcomes during left bundle branch area pacing with and without conduction system capture; Weiwei Zhang MD, Lu Chen MD, Xiaohong Zhou MD, Jingjuan Huang MD, PHD, Shiwei Zhu MD, E. Shen MD, Changqing Pan MD, Xumin Hou MD, PHD, Ruogu Li MD, PHD, Ben He MD, PHD; Clinical Cardiology, January 3, 2023, https://doi.org/10.1002/clc.23969

Left Bundle Branch Pacing Versus Biventricular Pacing for Acute Cardiac Resynchronization in Patients With Heart Failure; Yixiu Liang, Jingfeng Wang, Xue Gong, Hongyang Lu, Ziqing Yu, Lei Zhang, Minghui Li, Lei Pan, Xueying Chen, Jie Cui, Weiwei Zhang, Ruogu Li, Xiaohong Zhou, Weijian Huang, Yangang Su, Junbo Ge; Circulation: Arrhythmia and Electrophysiology. 28 Oct 2022, https://doi.org/10.1161/CIRCEP.122.011181;15

Randomized Trial of Left Bundle Branch vs Biventricular Pacing for Cardiac Resynchronization Therapy; Yao Wang MD, PhD, Haojie Zhu MD, Xiaofeng Hou MD, Zhao Wang MD, PhD, Fengwei Zou MD, Zhiyong Qian MD, PhD, Yongyue Wei MD, PhD, Xiang Wang BSc, Longyao Zhang, MD, XiaofeiLi, MD, Zhimin Liu, MD, Siyuan Xue, MD, Chaotong Qin, MD, Jiaxin Zeng, MD, Hui Li, MD, Hongping Wu, MD, Hong Ma, MD, Kenneth A. Ellenbogen, MD, Michael R. Gold, MD, PhD, Xiaohan Fan, MD, PhD, Jiangang Zou, MD, PhD; J Am Coll Cardiol, 2022 Sep, 80 (13) 1205–1216

Clinical Outcomes Of Conduction System Pacing Compared To Biventricular Pacing In Patients Requiring Cardiac Resynchronization Therapy; Pugazhendhi Vijayaraman, MD, FHR, Sab Dipen Zalavadia, MD, Abdul Haseeb, MD, Cicely Dye, MD, Nidhi Madan, MD, Jamario Renaldo Skeete, MD, Sharath C. Vipparthy, MD, Wilson Young, MD, PhD, Venkatesh Rav, MD, Clement Rajakumar, Parash Pokharel, MD, Timothy Larsen, DO, Henry D. Huang, MD, FHRS, Randle H. Storm, MD, FHR, SeJess W. Oren, MD, Syeda Atiqa Batul, MBBS, MD, Richard G. Trohman, BS, MBA, MD, FHRS, Faiz A.Subzposh, MD, Parikshit S. Sharma, MD, MPH, FHRS; Heart Rhythm, Available online 29 April 2022, https://doi.org/10.1016/j.hrthm.2022.04.023

Rescue Left Bundle Branch Area Pacing in Coronary Venous Lead Failure or Non-response to Biventricular Pacing: Results From International LBBAP Collaborative Study Group; Pugazhendhi Vijayaraman, MD, FHRS, Bengt Herweg, MD, FHRS2, Atul Verma, MD, FHRS3, Parikshit S. Sharma, MD, MPH, FHRS, Syeda Atiqa Batul, MBBS, MD, Shunmuga Sundaram Ponnusamy, MBBS, MD, CEPS, Robert D. Schaller, DO, FHRS, Oscar CanoMD, PhD, ManuelMolina-Lerma, MD, Karol Curila, MD, Wim Huybrechts, MD, David R.Wilson, MD, Leonard M. Rademakers, MD, PhD, Praveen, Sreekumar, MBBS, MD, Gaurav Upadhyay, MD, Kevin Vernooy, MD, PhD, Faiz A. Subzposh, MD, Weijian Huang, MD, FHRS, Kenneth A. Ellenbogen, MD, FHRS; Heart Rhythm, Available online 30 April 2022

First report of super-response after left bundle branch area pacing for cardiac resynchronization therapy utilizing a stylet-driven lead; Aalap Narichania, MD, Roderick Tung, MD, FACC, FHRS, Gaurav A. Upadhyay, MD, FACC, FHRS; Heart Rhythm, JANUARY 01, 2022, DOI:https://doi.org/10.1016/j.hrcr.2021.12.018

A Randomized Trial of His Pacing Versus Biventricular Pacing in Symptomatic HF Patients With Left Bundle Branch Block (His-Alternative); Michael Vinther, Niels Risum, Jesper Hastrup Svendsen, Rasmus Møgelvang, and Berit Thornvig Philbert; J Am Coll Cardiol EP. Jun 30, 2021, DOI: 10.1016/j.jacep.2021.04.003

LBB Area Pacing for Cardiac Resynchronization Therapy; Óscar Cano, MD; Pugazhendhi Vijayaraman, MD, FACC; JACC, Jan 25, 2021

His-Optimized Cardiac Resynchronization Therapy to Maximize Electrical Resynchronization; Pugazhendhi Vijayaraman, Bengt Herweg, Kenneth A. Ellenbogen, Jacek Gajek; Circulation: Arrhythmia and Electrophysiology. 2019;12:e006934

His-Optimized Cardiac Resynchronization Therapy With Ventricular Fusion Pacing for Electrical Resynchronization in Heart Failure; AlwinZweerinkMD, StepanZubarevMD, EliseBakelantsMD, DanilaPotyagayloPhD, CarineStettlerRN, MikhailChmelevskyMD, Elise DupuisLozeronPhD, Anne-LiseHachullaMD, Jean-PaulValléeMDeHaranBurriMD; JACC: Clinical Electrophysiology, Available online 24 February 2021

His bundle pacing shows similar ventricular electrical activation as sinus: selective and nonselective His pacing indistinguishable; Annie M. Hirahara,* Matthias Lange,* Ankur Shah, Muhammad S. Khan, Ravi Ranjan, Greg Stoddard, and Derek J. Dosdal; American Journal of Physiology, Heart and Circulatory Physiology, 29 DEC 2020 https://doi.org/10.1152/ajpheart.00292.2020

Electrocardiographic patterns predictive of left bundle branch block correction with His bundle pacing; Pablo Moriña‐Vázquez, Maria Teresa Moraleda‐Salas, Álvaro Arce‐León, Juan Manuel Fernández‐Gómez, José Venegas‐Gamero, José Francisco Díaz‐Fernández; PACE, 28 July 2020 https://doi.org/10.1111/pace.14021

Left bundle branch pacing: A comprehensive review; Shunmuga Sundaram Ponnusamy, Vanita Arora, Narayanan Namboodir, Vivek Kumar, Aditya Kapoor, Pugazhendhi Vijayaraman; J Cardiovasc Electrophysiol, 2020 Jul 18. doi: 10.1111/jce.14681

His Bundle and Left Bundle Pacing with Optimised Atrio-ventricular Delay Achieve Superior Electrical Synchrony over Endocardial and Epicardial Pacing in Left Bundle Branch Block Patients; Marina Strocchi, MSc, Angela W.C. Lee, PhD, Aurel Neic, PhD, Edward J. Vigmond, PhD, Christopher A. Rinaldi, MBBS, MD, FHRS, Steven A. Niederer, PhD; Heart Rhythm Open AccessPublished:June 27, 2020, DOI:https://doi.org/10.1016/j.hrthm.2020.06.028

Left bundle branch pacing for Cardiac Resynchronization Therapy: Non-randomized on treatment comparison with His Bundle Pacing and Biventricular Pacing; Shengjie Wu, MD, Lan Su, MD, Pugazhendhi Vijayaraman, MD, Rujie Zheng, MD, Mengxing Cai, MD, Lei Xu, MD, Ruiyu Shi, MD, Zhouqing Huang, MD, Zachary I. Whinnett, BM BS PHD, Weijian Huang, MD; Published: May 06, 2020, DOI:https://doi.org/10.1016/j.cjca.2020.04.037

Keeping Pace With the Competition: His Bundle Versus Biventricular Pacing in Heart Failure; Gaurav A Upadhyay 1, Roderick Tung; PMID: 32205478 DOI: 10.1097/HCO.0000000000000735; Mar 19, 2020

On-treatment comparison between corrective His bundle pacing and biventricular pacing for cardiac resynchronization: A secondary analysis of the His-SYNC Pilot Trial: Gaurav A. Upadhyay, MD, FHRS, Pugazhendhi Vijayaraman, MD, FHRS, Hemal M. Nayak, MD, FHRS, Nishant Verma, MD, MPH, Gopi Dandamudi, MD, FHRS, Parikshit S. Sharma, MD, FHRS, Moeen Saleem, MD, John Mandrola, MD, Davide Genovese, MD, Jess W. Oren, MD, Faiz A. Subzposh, MD, Zaid Aziz, MD, Andrew Beaser, MD, Dalise Shatz, BA, Stephanie Besser, MSAS, Roberto M. Lang, MD, Richard G. Trohman, MD, FHRS#, Bradley P. Knight, MD, FHRS, Roderick Tung, MD, FHRS; HeartRhythm, December 2019Volume 16, Issue 12, Pages 1797–1807

His Corrective Pacing or Biventricular Pacing for Cardiac Resynchronization in Heart Failure; Gaurav A. Upadhyay, Pugazhendi Vijayaraman, Hemal M. Nayak, Nishant Verma, Gopi Dandamudi, Parikshit S. Sharma, Moeen Saleem, John Mandrola, Davide Genovese, Roderick Tung and on behalf of the His-SYNC Investigators; Journal of the American College of Cardiology, May 2019, DOI: 10.1016/j.jacc.2019.04.026

How to Choose Between His Bundle Pacing and Biventricular Pacing for Cardiac Resynchronization Therapy; Gaurav A. Upadhyay, Pugazhendhi Vijayaraman; Current Cardiovascular Risk Reports 13(3), March 2019, DOI: 10.1007/s12170-019-0598-9

Intracardiac Delineation of Septal Conduction in Left Bundle Branch Block Patterns: Mechanistic Evidence of Left Intra-Hisian Block Circumvented by His Pacing; Gaurav A. Upadhyay , Tharian Cherian , Dalise Y. Shatz , Andrew D. Beaser , Zaid Aziz , Cevher Ozcan , Michael T. Broman , Hemal Nayak , and Roderick Tung; https://doi.org/10.1161/CIRCULATIONAHA.118.038648Circulation. 2019;0; 1 Feb 2019

His Resynchronization Versus Biventricular Pacing in Patients With Heart Failure and Left Bundle Branch Block; Ahran D. Arnold, Matthew J. Shun-Shin, Daniel Keene, James P. Howard, S.M. Afzal Sohaib, Ian J. Wright, Graham D. Cole, Norman A. Qureshi, David C. Lefroy, Michael Koa-Wing, Nick W.F. Linton, Phang Boon Lim, Nicholas S. Peters, D. Wyn Davies, Amal Muthumala, Mark Tanner, Kenneth A. Ellenbogen, Prapa Kanagaratnam, Darrel P. Francis and Zachary I. Whinnett; Journal of the American College of Cardiology, Volume 72, Issue 24, December 2018, DOI: 10.1016/j.jacc.2018.09.073

2018 Top Stories in Cardiology: The Benefits of His Bundle Pacing; Douglas P Zipes MD; Cardiology, November 09, 2018

Permanent His Bundle Pacing for Cardiac Resynchronization Therapy in Patients With Heart Failure and Right Bundle Branch Block; Parikshit S. Sharma , Angela Naperkowski , Terry D. Bauch , Joseph Y.S. Chan , Ahran D. Arnold , Zachary I. Whinnett , Kenneth A. Ellenbogen , and Pugazhendhi Vijayaraman; Circ Arrhythm Electrophysiol. 2018;11:e006613. DOI: 10.1161/CIRCEP.118.006613 September 2018

Reversal of left bundle branch block–induced cardiomyopathy by His bundle pacing; Liu F, Zeng L, Yin X, Gao L, Xia Y, Dong Y; Journal of International Medical Research, November 4, 2019

Left ventricular regional remodeling and lead position during cardiac resynchronization therapy; Mads Brix Kronborg, MD, PhD, Anders Sommer, MD, PhD, Daniel B. Fyenbo, XX, Bjarne L. Norgaard, MD, PhD, Christian Gerdes, MD, PhD, Jesper Moller Jensen, MD, PhD, Henrik Kjærulf Jensen, MD, DMSc, Jens Kristensen, MD, PhD, Jens C. Nielsen, MD, DMSc, Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus N, Denmark; Heart Rhythm, Published online: April 17, 2018

His Bundle Pacing Or Biventricular Pacing For Cardiac Resynchronization Therapy In Heart Failure: Discovering New Methods For An Old Problem; Sharma PS, Vijayaraman P; Rush University Medical Center, Chicago, IL and Geisinger Heart Institute, Wilkes Barre, PA.; J Atr Fibrillation, 2016 Dec 31

His-Bundle Pacing Excels as Primary CRT Alternative in Large Series; Steve Stiles; Medscape; February 8, 2018

Permanent His Bundle Pacing (HBP): Recommendations From A Multi-Center HBP Collaborative Working Group For Standardization Of Definitions, Implant Measurements And Follow-Up; Pugazhendhi Vijayaraman, MD, FHRS, Gopi Dandamudi, MD, FHRS, Francesco Zanon, MD, FHRS, Parikshit S. Sharma, MD, MPH, Roderick Tung, MD, FHRS, Weijian Huang, MD, FHRS, Jayanthi Koneru, MBBS, Hiroshi Tada, MD, PhD, FHRS, Kenneth A. Ellenbogen, MD, FHRS, Daniel L. Lustgarten, MD, PhD, FHRS; DOI: http://dx.doi.org/10.1016/j.hrthm.2017.10.039

Permanent His Bundle Pacing as an Alternative to Biventricular Pacing for Cardiac Resynchronization Therapy: A Multi-Center Experience; Parikshit S. Sharma, MD, MPH, FACC, Gopi Dandamudi, MD, FHRS, Bengt Herweg, MD, David Wilson, MD, Rajeev Singh, MD, Angela Naperkowski, RN, FHRS, CCDS, CEPS, Jayanthi N. Koneru, MBBS, Kenneth A. Ellenbogen, MD, FACC, FHRS, Pugazhendhi Vijayaraman, MD, FACC, FHRS; DOI: http://dx.doi.org/10.1016/j.hrthm.2017.10.014

His-Bundle Pacing for CRT: Has It Finally Hit Critical Mass?; Patrice Wendling; Medscape; April 21, 2017

Permanent His-bundle pacing for cardiac resynchronization therapy: Initial feasibility study in lieu of left ventricular lead; Ajijola O, MD, PhD, Upadhyay G, MD, FHRS, Macias C, MD, Shivkumar K, MD, PhD, FHRS, Tung R, MD, FHRS; Heart Rhythm Journal, September 2017, Vol 14, Issue 9, Pages 1353–1361

Cardiac resynchronization therapy using permanent His-bundle pacing: Are we there yet?; Vijayaraman P, MD, FHRS; Grisinger Heart Institute, Wilkes-Barre, PA; Heart Rhythm Journal, Sep 2017, Vol 14, Issue 9, Pages 1362–1363

Physiological mechanisms of QRS narrowing in bundle branch block patients undergoing permanent His bundle pacing; Alexandra E. Teng, MD, Louis Massoud, Olujimi A. Ajijola, MD, PhD; UCLA Cardiac Arrhythmia Center, Los Angeles, CA; Journal of Electrocardiology (2016)

Functional aspects of His bundle physiology and pathophysiology: Clinical implications; Benjamin. Scherlag, PhD, Ralph Lazzara, MD Heart Rhythm Institute, Division of Cardiology, Department of Medicine, Oklahoma University Health Sciences Center, Oklahoma City, OK; Journal of Electrocardiology (2016)

Usefulness of His Bundle Pacing to Achieve Electrical Resynchronization in Patients With Complete Left Bundle Branch Block and the Relation Between Native QRS Axis, Duration, and Normalization; Alexandra E. Teng, MDa, Daniel L. Lustgarten, MD, PhDb, Pugazhendhi Vijayaraman, MDc, Roderick Tung, MDd, Kalyanam Shivkumar, MD, PhDa, Galen S. Wagner, MDe, Olujimi A. Ajijola, MD, PhDa;, a University of California Los Angeles Cardiac Arrhythmia Center, Los Angeles, California, b, University of Vermont Medical Center, Burlington, Vermont, c Geisinger Medical Center, Wilkes-Barre, Pennsylvania, d University of Chicago Heart Rhythm Center, Chicago, Illinois, e Duke University School of Medicine, Durham, North Carolina; The American Journal of Cardiology, Volume 118, Issue 4, 15 August 2016, Pages 527–534

Intermittent Capture of the Left Bundle With Permanent His Bundle Pacing: Mechanistic Insights and Implications for an Emerging Field; Friedman DJ¹, Hjorth MA², Sun AY^1,3, Atwater BD^1,3, ¹Division of Electrophysiology, Duke University Hospital, Durham, North Carolina, USA., ²Karolinska Institute, Stockholm, Sweden, ³Durham Veterans Administration Hospital, Durham, North Carolina, USA.; , 2016 Aug 1. doi: 10.1111/jce.13057

His-Bundle vs Biventricular Pacing in Resynchronization Therapy; Lustgarten, Daniel, MD, PHD, FHRS, Crespo, Eric, MD, MPH, FHRS, Arkhpova-Jenkens, Irina, MD, Lobel, Robert, MD, Winget, Jopseph, MD, Koehler, Jodi, MS, Liberman, Evan, BS, Sheldon, Todd, MS; Heart Rhythm Journal, July 2015, Vol 12, Issue 7, Pages 1548–1557

Direct His Bundle Pacing vs. BiVentricular Pacing in CRT Patients – A Cross-over Design Comparison; Lustgarten, Daniel, MD, PHD, FHRS, Correa de Sa, Daniel, MD, Lobel, Robert, MD, Sheldon, Todd, MS, Crespo, Eric, MD, MPH, FHRS; Heart Rhythm on Demand 2013, The University of Vermont, Burlington, VT, Medtronic, Inc., Minneapolis, MN, Hartford Hospital, Hartford, CT

Selective His Pacing Shortens Intraventricular Conduction Compared to Intrinsic Conduction in Patients with Left Bundle Branch Block; Niazi I, Hayes C, Dahme R, Fedewa M, Pappelbaum B, Sta J,Akhtar M; Heart Rhythm 2011, Vol 8, No. 5, May Supplement 2011

Cardiac Resynchronization Through Selective His Bundle Pacing in a Patient with the So-Called InfraHis Atrioventricular Block; Morina-Vasquez, Pablo, Rafael Barba-Pichardo, Jose Venegas-Gamero, Manuel Herrera-Carranza; PACE, 2005; 28: 726-729.

Permanent His-Bundle Pacing in patients with Infra-Hisian Atrioventricular Block; Barba-Pichardo, Rafael, Pablo Morina-Vasquez, Jose Venegas-Gamero, Fernando Maroto-Monserrat, Manuela Cid-Cumplido, Manuel Herrera-Carranza; Revista Espanola de Cardiologia; 2006; 59(6):553-8

Direct His Bundle Pacing Results in Significant QRS Narrowing in Patients Referred For Cardiac Resynchronization Therapy; Daniel L. Lustgarten, MD, PhD, Susan Neal, RN, Eric Crespo, MD, MPH, Robert Lobel, MD, Peter Spector, MD and Peter Van Buren, MD. U of VT, Burlington, VT; Heart Rhythm 2009, Presentation Abstract, May 14, 2009

Comparison of Direct His Bundle and Biventricular Pacing; Pramod M. Deshmukh, MD, Amrish Deshmukh, No Degree, Mary Romanyshyn, CRNP, Kathleen Anderson, BSN, David Lahoda, BSN, Patricia Lambert, RDCS andZara Babayan, MD. Guthrie Clinic, Ltd., Sayre, PA, Cornell University, Ithaca, NY; Heart Rhythm 2009, Poster Session V, May 15, 2009

Pacing and sensing optimization of permanent His-bundle pacing in cardiac resynchronization therapy/implantable cardioverter defibrillators patients: value of integrated bipolar configuration; Lan Su, Lei Xu, Sheng-jie Wu, Wei-jian Huang; EP Europace, Volume 18, Issue 9, Pp. 1399 – 1405

Direct His Bundle Pacing in a Patient with Complete Heart Block Requiring Implantable Defibrillator; Worsnick, PA-C, Campagna, NP, Lacey, PA-C, Dandamudi, MD, FHRS, Vijayaraman, MD, FHRS; The Journal of Innovation in Cardiac Rhythm Management, Aug. 2013, 492

Direct His-Bundle Triple Site Pacing: A Novel Alternative to Bi-Ventricular Pacing; Pramod M. Deshmukh, MD, Amrish Deshmukh, No Degree, Mary Romanyshyn, CRNP and Kathleen Anderson, BSN. Guthrie Clinic, Ltd., Sayre, PA, Cornell University, Ithaca, NY; Heart Rhythm 2009, Presentation Abstract, May 14, 2009

Longitudinal Dissociation in the His Bundle; Narula, Onkar S, M.D.; Circulation December, 1977; vol. 56, No 6; 996-1006.

Normalization of Bundle Branch Block Patterns by Distal His Bundle Pacing. Clinical and Experimental Evidence of Longitudinal Dissociation in the Pathologic His Bundle; El-Sherif N, Amay YLF, Schonfield C, Scherlag BJ, Rosen K, Lazzara R, Wyndham; C.Circulation; 1978; 57:473-83.

If I have heart failure subsequent to conventional pacing, can my heart heal itself if I convert to His bundle pacing?

Reconstitution of native intrinsic conduction in patients with chronic conduction block with His bundle pacing; Fatima M. Ezzeddine, MD, Rajeev Singh, MD, Samuel J. Asirvatham, MD, FHRS, Gopi Dandamudi, MD, FHRS, Subodh R. Devabhaktuni, MD, FACC, FHRS; HeartRhythm, March 23, 2021DOI:https://doi.org/10.1016/j.hrcr.2021.03.006

Reconstitution of native intrinsic conduction in patients with chronic conduction block with His bundle pacing; Fatima M. Ezzeddine, MD, Rajeev Singh, MD, Samuel J. Asirvatham, MD, FHRS, Gopi Dandamudi, MD, FHRS, Subodh R. Devabhaktuni, MD, FACC, FHRS; HeartRhythm, Published:March 23, 2021DOI:https://doi.org/10.1016/j.hrcr.2021.03.006

Outcomes of His-bundle pacing upgrade after long-term right ventricular pacing and/or pacing-induced cardiomyopathy: Insights into disease progression; Pugazhendhi Vijayaraman, MD, FHRS, Bengt Herweg, MD, FHRS, Gopi Dandamudi, MD, FHRS, Suneet Mittal, MD, FHRS, Advay G. Bhatt, MD, Lina Marcantoni, MD, Angela Naperkowski, RN, CCDS, CEPS, FHRS, Parikshit S. Sharma, MD, MPH, FHRS, Francesco Zanon, MD, FESC; HeartRhythm Case Reports, October 2019Volume 16, Issue 10, Pages 1554–1561, DOI: https://doi.org/10.1016/j.hrthm.2019.03.026

Beneficial effects of upgrading to His bundle pacing in chronically paced patients with left ventricular ejection fraction <50%; Shan, MD, Peiren; Su, MD, Lan; Zhou, MD, Xiaodong; Wu, MD, Shengjie; Xu, MD, Lei; Xiao, MD, Fangyi;Zhou, MD, Xiaohong; Ellenbogen, Kenneth A, MD, FHRS, Huang, Weijian, MD, FHRS; Heart Rhythm, March 2018, Volume 15, Issue 3, Pages 405–412

Reversal of Left Ventricular Dysfunction with Biventricular or His-bundle Pacing Upgrade Late after A-V Nodal Ablation/block; Hoyt, Robert H., M.D., McHenry, Brian T, MSME; Heart Rhythm 2008 29th Scientific Sessions

MY APPROACH to Choosing Ventricular Pacing Sites in Patients With Severe Heart Failure; Gopi Dandamudi, MD; Indiana University School of Medicine, Indianapolis; Cardiology, October 03, 2016

Physiologic Resynchronization Therapy: A Case of His Bundle Pacing Reversing Physiologic Conduction in a Patient With CHF and LBBB During 2 Years of Observation; Dabrowski, Papel, M.D., Kleingok, Andrzej, Ph.D., Kozluk, Edward, M.D.,Opolski, Gregorz, Ph.D; Journal of Cardiovascular Electrophysiology; Volume 22, Issue 7, pages 813–817, July 2011

Permanent, Direct His-bundle Pacing: A Novel Approach to Cardiac Pacing in Patients with Normal His-Purkinje Activation; Deshmukh, P, Casavant DA, Romanyshyn M, Anderson K.; Circulation 2000; 101: 869-877

I have persistent atrial fibrillation. Is ablation of the AV node, followed by His bundle pacing, a heart healthy, viable option?

His-bundle pacing and atrioventricular nodal ablation for noncontrolled atrial arrhythmia: A technical challenge with major clinical benefits; Corentin Chaumont MD, FHRS. Nathanael Auquier MD. Antoine Milhem MD. Adrian Mirolo MD, Alain Al Arnaout MD. Elena Popescu MD. Alix Algrin MD. Valentin Dupasquier MD. Guillaume Viart MD. Bénédicte Godin MD. Arnaud Savouré MD. Hélène Eltchaninoff MD, PhD. Frédéric Anselme MD, PhD; Heart Rhythm, Vol 20, Iss 4, April 2023, Pages 530-536

His Bundle Pacing and AV nodal ablation for non-controlled atrial arrhythmia: a technical challenge with major clinical benefits; Corentin Chaumont MD, Nathanael Auquier MD, Antoine Milhem MD, Arnaud Savouré MD, Hélène Eltchaninoff MD PhD, Frédéric Anselme MD PhD; Heart Rhythm, December 19, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.12.022

Conduction system pacing versus conventional pacing in patients undergoing atrioventricular node ablation: Nonrandomized, on-treatment comparison; Pugazhendhi Vijayaraman MD, FHRS, Andrew J. Mathew MD, Angela Naperkowski RN, CEPS, CCDS, FHRS, Wilson Young MD, Parash Pokharel MD, Syeda A. Batul MD, Randle Storm MD, FHRS, Jess W. Oren MD, Faiz A. Subzposh MD; Heart Rhythm O2, Vol 3, Issue 4, August 2022, Pages 368-376

Atrioventricular junction ablation in patients with conduction system pacing leads: A comparison of His-bundle vs left bundle branch area pacing leads; Ajay Pillai, MD, Jeffrey Kolominsky, MD, Jayanthi N. Koneru, MD, Jordana Kron, MD, Richard K. Shepard, MD, Gautham Kalahasty, MD, Weijian Huang, MD, Atul Verma, MD, FHRS, Kenneth A. Ellenbogen, MD, FHRS, Heart Rhythm, March 26, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.03.1222

His Bundle Pacing vs Biventricular Pacing Following Atrioventricular Node Ablation in Patients with Atrial Fibrillation and Reduced Ejection Fraction: A Multicenter, Randomized, Crossover Study. The ALTERNATIVE-AF trial; Weijian Huang, MD, Songjie Wang, MD, Lan Su, MD, Guangyun Mao, MD, Kenneth A. Ellenbogen, MD, Zachary I. Whinnett, MD, PhD; Heart Rhythm, July 13, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.07.009

Atrioventricular Junction Ablation in Patients with the Conduction System Pacing Leads: A Comparison of His Bundle vs Left Bundle Branch Area Pacing Leads; Ajay Pillai, MD, Jeffrey Kolominsky, MD, Jayanthi N. Koneru, MD, Jordana Kron, MD, Richard K. Shepard, MD. Gautham Kalahasty, MD, Weijian Huang, MD, Atul Verma, MD, Kenneth A. Ellenbogen, MD; March 26, Heart Rhythm, 2022, DOI: https://doi.org/10.1016/j.hrthm.2022.03.1222

Effectiveness and safety of AV node ablation after His bundle pacing in patients with uncontrolled atrial arrhythmias; Pablo Moriña-Vázquez, María Teresa Moraleda-Salas, Álvaro Arce-León, José Venegas-Gamero, Juan Manuel Fernández-Gómez, José Francisco Díaz-Fernández; Pacing and Clinical Electrophysiology, 26 April 2021, https://doi.org/10.1111/pace.14252

His‐bundle pacing as a standard approach in patients with permanent atrial fibrillation and bradycardia; Marek Jastrzębski MD, PhD Paweł Moskal MD Agnieszka Bednarek MD, PhD Grzegorz Kiełbasa MD Danuta Czarnecka MD, PhD; PACE, Volume41, Issue11, November 2018, Pages 1508-1512

Benefits of Permanent His Bundle Pacing Combined With Atrioventricular Node Ablation in Atrial Fibrillation Patients With Heart Failure With Both Preserved and Reduced Left Ventricular Ejection Fraction; Huang W^1,2, Su L^3,2, Wu S^3,2, Xu L^3,2, Xiao F^3,2, Zhou X⁴, Ellenbogen KA⁵, ¹Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China weijianhuang69@126.com, ²The Key Lab of Cardiovascular Disease of Wenzhou, Wenzhou, China, ³Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China, ⁴Cardiac Rhythm and Heart Failure Division, Medtronic, Mounds View, MN, ⁵Department of Cardiology, Virginia Commonwealth University Health System, Richmond, VA; J Am Heart Assoc, 2017 Apr 1;6(4). pii: e005309. doi: 10.1161/JAHA.116.005309

Permanent His bundle pacing – An optimal treatment method in heart failure patients with AF and narrow QRS; Sławuta A¹, Mazur G², Małecka B³, Gajek J⁴, ¹Department of Cardiology, Klodzko County Hospital, Kłodzko, Poland, ²Department of Internal and Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland,.³Institute of Cardiology, Jagiellonian University Medical College, Kraków, Poland, ⁴Department of Cardiology, Wroclaw Medical University, Wrocław, Poland. Electronic address: jacek.gajek@interia.pl, Int J Cardiol. 2016 Jul 1;214:451-2. doi: 10.1016/j.ijcard.2016.04.022. Epub 2016 Apr 8.

Rate Stabilization By Right Ventricular Apex or His Bundle Pacing in Patients With Atrial Fibrillation; Padeletti, Luigi, Fabio Fantini, Antonio Michelucci, Paolo Pieragnoli, Andrea Colella, Nicola Musilli, Guiseppe Ricciardi, Trina A Buhr, Sergio Valsecchi; Europace 2005; 7:454-459

Permanent His-Bundle Pacing After Atrioventricular Node Ablation in a Patient With Chronic Atrial Fibrillation and Mitral Regurgitation, Yamauchi Y, Aonuma K, Hachiya H, Isobe M; Circ J 2005; 69:510-514

Prevention of Ventricular Desynchronization by Permanent Para-Hisian Pacing after Atrioventricular Node Ablation in Chronic Atrial Fibrillation; a crossover, blinded, randomized study versus apical right ventricular pacing; Occhetta E, MD, Bortnik M, MD, Magnani, A, MD, Francalacci, G. MD, Piccinino, C. MD, Plebani, L, PhD, Marino, P, MD, FESC; Journal of the American College of Cardiology, May 16, 2006, Vol. 47, No. 10, 1938-45

Comparison of Lead Placement Strategies for Permanent His Bundle Pacing; Niazi I, Indrajit C, Sra J, Akhtar M; Heart Rhythm, Vo. 8, No. 5, May Supplemant 2011

Direct His-bundle Pacing in Patients Following AV Node Ablation; Znojkiewicz P, Calame S, Lobel R, Lustgarten D; Heart Rhythm 2011, Vol. 8, No. 5, May Supplement 2011

Atrial Fibrillation After DDDR Pacemaker Implantation; Anne M. Gillis M.D., Margaret Morck B.A., R.N.; Cardiovascular Research Group and the Division of Cardiology, The University of Calgary and Foothills Medical Centre, Alberta, Canada; J Cardiovasc Electrophysiol. 2002 Jun;13(6):542-7

Implant considerations, and can the His or LBB pacing implant procedure be done quickly and easily compared with conventional pacing?

Feasibility and Efficacy of dual cathode modality in left bundle branch pacing; Wei Tang, MD, Wei He, MD, Ming Long, MD, Rongxuan Chang, MD, Chen Su, MD, Jie Li, MD, Menghui Liu, MD, Xiaoyu Zhang, MD, Xumiao Chen, MD, Jingzhou Jiang, MD, Donghong Liu, MD, Lichun Wang, MD; Heart Rhythm, September 05, 2023, DOI:https://doi.org/10.1016/j.hrthm.2023.08.038

Bipolar anodal septal pacing with direct LBB capture preserves physiological ventricular activation better than unipolar left bundle branch pacing; Karol Curila, Pavel Jurak, Frits Prinzen, Marek Jastrzebski, Petr Waldauf, Josef Halamek, Marketa Tothova, Lucie Znojilova, Radovan Smisek, Jakub Kach, Lukas Poviser, Hana Linkova, Filip Plesinger, Pawel Moskal, Ivo Viscor, Vlastimil Vondra, Pavel Leinveber, Pavel Osmancik; Front Cardiovasc Med., 2023; 10: 1140988, Published online 2023 Mar 22. doi: 10.3389/fcvm.2023.1140988

The 10 commandments for setting up a successful conduction system pacing program; Haran Burri, Cardiology Department, University Hospital of Geneva, Geneva, Switzerland, Available online 21 March 2023

Left bundle area pacing: Guiding implant depth by ring measurements; Michael V. Orlov, MD, PhD. Marianna Nikolaychuk, MD. Ioannis Koulouridis, MD, Alena Goldman, MD. Shaw Natan, MD. James Armstrong, PA. Adhiraj Bhattacharya, MD. Amy Hicks, RTR. Michael King, RTR. John Wylie, MD; Heart Rhythm, Jan 2023, Vol 20, Iss 1, P55-60

Simplifying follow-up of left bundle branch pacing leads: Assessment of left bundle branch capture using a programmer only; Eugene S.J. Tan, MBBS. Jie-Ying Lee, BSc, Siew Pang Chan, PhD, Elaine Boey, MBBS, Swee-Chong Seow, MBBS, FHRS, Pipin Kojodjojo, MBBS, PhD, FHRS; Heart Rhythm Journal, .Jan 30, 2023 https://doi.org/10.1016/j.hrthm.2023.01.031

Effect of scar and His–Purkinje and myocardium conduction on response to conduction system pacing; Marina Strocchi PhD, Karli Gillette PhD, Aurel Neic PhD, Mark K. Elliott MBBS, Nadeev Wijesuriya MBBS, Vishal Mehta MBBS, Edward J. Vigmond PhD, Gernot Plank PhD, Christopher A. Rinaldi MBBS, MD, FHRS, Steven A. Niederer PhD; Journal of Cardiovasc Electrophysiol, Feb 4, 2023, doi: 10.1111/jce.15847

Biventricular endocardial pacing and left bundle branch area pacing for cardiac resynchronization: Mechanistic insights from electrocardiographic imaging, acute hemodynamic response, and magnetic resonance imaging; Mark K. Elliott MBBS, Marina Strocchi PhD, Benjamin J. Sieniewicz MBChB PhD, Tom Wong MD FHRS, Steven Niederer PhD, Christopher A. Rinaldi MD FHRS; Heart Rhythm, February 2023, Vol 20, Issue 2, P207-216

Masked right bundle branch conduction delay pattern during left bundle branch pacing; Pugazhendhi Vijayaraman MD, Shunmuga Sundaram Ponnusamy MD; Heart Rhythm, August 05, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.07.029

New criterion to determine left bundle branch capture on the basis of individualized His bundle or right ventricular septal pacing; Zhiyong Qian MD PhD, Siyuan Xue MD, Fengwei Zou MD, Chaotong Qin MD, Yao Wang MD PhD, Xinwei Zhang MD PhD, Yuanhao Qiu MD PhD, Hongping Wu MD, Xiaofeng Hou MD, Jiangang Zou MD PhD FHRS; Heart Rhythm, Vol 19, Issue 12, December 2022, Pages 1984-1992

Electrophysiological characteristics and possible mechanism of bipolar pacing in left bundle branch pacing; Hao Wu, MD, Longfu Jiang, MD, Jiabo Shen, MD, Lu Zhang, MD, Jinyan Zhong, MD, Shanshan Zhuo, MD; Heart Rhythm, June 16, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.06.022

Predictors of loss of capture in left bundle branch pacing: A multicenter experience, Eugene S.J. Tan, MBBS, Jie-Ying Lee, BS, Elaine Boey, MBBS, Rodney Soh, MBBS, Swee-Chong Seow, MBBS, FHRS, Lisa J.T. Teo, BS, Colin Yeo, MBBS, Vern Hsen Tan, MBBS, Pipin Kojodjojo, MBBS, PhD, FHRS; Heart Rhythm, June 07, 2022, DOI:https://doi.org/10.1016/j.hrthm.2022.06.003

Permanent His-bundle pacing using stylet-directed, active-fixation leads placed via coronary sinus sheaths compared to conventional lumen-less system; Michael V. Orlov MD, PhD, David Casavant MS, Ioannis Koulouridis, MD, MS, Mikhail Maslov, MD, Aharon Erez, MD, Amy Hicks, RT, Ahad Jahangir, MS, Joe Aoun, MD, John V. Wylie, MD; Heart Rhythm, Volume 16, Issue 12, December 2019, Pages 1825-1831

Can permanent His bundle pacing be safely started by operators new to this technique? Data from a multicenter registry; Corentin Chaumont, Nathanael Auquier, Antoine Milhem, Adrian Mirolo, Alain Al Arnaout, Elena Popescu, Guillaume Viart, Bénédicte Godin, André Gillibert, Arnaud Savouré, Hélène Eltchaninoff, Frédéric Anselme; J Cardiovasc Electrophysiol, 2021 Feb;32(2):417-427. doi: 10.1111/jce.14860. Epub 2021 Jan 9

His-Purkinje Conduction System Pacing in Atrioventricular Block: New Insights into Site of Conduction Block; Pugazhendhi Vijayaraman, MD, Neil Patel, MD, MPH, Shaun Colburn, MD, Dominik Beer, MD, Angela Naperkowski, RN, CCDS, CEPS, Faiz A. Subzposh MD; JACC: Clinical Electrophysiology (Available online 27 July 2021)

Deep septal, distal His bundle pacing to achieve low and stable capture threshold; Yoji Iida, MD, Tomoaki Izawa, MD, Chikara Kobari, MD, Toru Yatsuhashi, MD, Nobuyuki Makishima, MD; HeartRhythm, October 15, 2020 DOI:https://doi.org/10.1016/j.hrcr.2020.10.005

His-Purkinje Conduction System Pacing Following Transcatheter Aortic Valve Replacement, Pugazhendhi Vijayaraman, Óscar Cano, Jacob S. Koruth, Faiz A. Subzposh, Sudip Nanda, Jessica Pugliese, Venkatesh Ravi, Angela Naperkowski and Parikshit S. Sharma, JACC: Clinical Electrophysiology, Volume 6, Issue 6, June 2020, DOI: 10.1016/j.jacep.2020.02.010

Electrogram‐only guided approach to His bundle pacing with minimal fluoroscopy: A single-center experience; Francesco Zanon MD, FESC, FHERA, FHRA, Lina Marcantoni MD Marco Zuin MD Gianni Pastore MD Enrico Baracca MD Antonella Tiribello RN Paola Raffagnato RN Graziano Boaretto BS Loris Roncon MD Pugazhendhi Vijayaraman MD; J Cardiovasc Electrophysiol. 2020 Jan 24. doi: 10.1111/jce.14366. [Epub ahead of print]

Imaging-Based Localization of His Bundle Pacing Electrodes: Results From the Prospective IMAGE-HBP Study; Pugazhendhi Vijayaraman, Gopi Dandamudi, Faiz A. Subzposh, Richard K. Shepard, Gautham Kalahasty, Santosh K. Padala, John S. Strobel, Terry D. Bauch, Kenneth A. Ellenbogen, Tracy Bergemann, Lisa Hughes, Megan L. Harris, Dedra H. Fagan, Zhongping Yang, Jayanthi N. Koneru; J Am Coll Cardiol EP, 2021 Jan, 7 (1) 73–84

A feasible approach for His bundle pacing using a novel mapping system in patients receiving pacemaker therapy; Wei Hua, MD, FHRS, Yi-ran Hu, MD, Min Gu, MD, Chi Cai, MD, Xu-hua Chen, MD, Hong-xia Niu, MD, and Shu Zhang, MD, FHRS; State Key Laboratory of Cardiovascular Disease, Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; HeartRhythm Case Rep. 2019 Aug; 5(8): 433–435, Published online 2019 Jun 21. doi: 10.1016/j.hrcr.2019.06.003

Learning Curve and Initial Experience With Implementation of a His-Bundle Pacing Program in an Australian Setting; Luke P.DawsonMBBS, MPH, Julie CaddenMBBS, DerkPo lMBBS, Gareth Wynn MBChB, MD(Res) Leeanne Grigg MBBS, Jonathan Kalman MBBS, PhD, Irene Stevenson MBBS; Department of Cardiovascular Medicine, Royal Melbourne Hospital, Melbourne, Vic, Australia, Department of Medicine, University of Melbourne, Melbourne, Vic, Australia; Heart, Lung and Circulation, Available online 30 January 2020

Anatomical Considerations for His Bundle Pacing; Venkat D. Nagarajan , Siew Yen Ho , Sabine Ernst; Circulation: Arrhythmia and Electrophysiology, Vol. 12, No. 7, https://doi.org/10.1161/CIRCEP.118.006897

Extraction of the permanent His bundle pacing lead: Safety outcomes and feasibility of reimplantation; PugazhendhiVijayaramanMD, FHRS Faiz A.SubzposhMD AngelaNaperkowskiRN, CEPS, CCDS, FHRS; Heart Rhythm, 2019 Jun 12, DOI: https://doi.org/10.1016/j.hrthm.2019.06.005

His bundle has a shorter chronaxie than does the adjacent ventricular myocardium: Implications for pacemaker programming; Marek Jastrzębski, MD, PhD, Agnieszka Bednarek, MD, Ph∗, Grzegorz Kiełbasa, MD, Pugazhendhi Vijayaraman, MD, FHRS, Danuta Czarnecka, MD, PhD; HeartRhythm, DOI: https://doi.org/10.1016/j.hrthm.2019.06.001

His bundle pacing in Ebstein’s anomaly; Louise Segan, Mark Perrin, Jessica Thomas, and Daryl Ridley; Department of Cardiology, Barwon Health, Ryrie Street, Geelong VIC 3220, Australia

His bundle pacing, learning curve, procedure characteristics, safety and feasibility: insights from a large international observational study; Daniel Keene MbCHb MSc Ahran D Arnold MBBS Marek Jastrzębski MD PhD Haran Burri MD Steven Zweibel MD Eric Crespo MD Badrinathan Chandrasekaran MD Sukhbinder Bassi MD Nader Joghetaei MD Matthew Swift BSc Pawel Moskal MD Darrel P Francis MD Paul Foley MD Matthew J Shun‐Shin PhD Zachary I Whinnett PhD; Journal of Cardiovascular Electrophysiology, 16 July 2019, https://doi.org/10.1111/jce.14064

Permanent His-bundle pacing from the right atrium in patients with prosthetic tricuspid valve; Stephanie C. Fuentes Rojas, MD, Paul A. Schurmann, MD, Moisés Rodríguez-Mañero, MD, PhD‡, Daniel Lustgarten, MD, PhD, FHRS, Miguel Valderrábano, MD, FACC; HeartRhythm Journal, May 2019Volume 5, Issue 5, Pages 244–246, DOI: https://doi.org/10.1016/j.hrcr.2019.01.009

How to perform permanent His bundle pacing in routine clinical practice; Pugazhendhi Vijayaraman, M.D.* and Gopi Dandamudi, M.D.†; *Division of Cardiac Electrophysiology, Geisinger Heart Institute, Wilkes-Barre, Pennsylvania, †Indiana University School of Medicine, Indianapolis, Indiana; Heart Rhythm, June 2016,Volume 13, Issue 6, Pages 1362–1366

Permanent His bundle pacing: shaping the future of physiological ventricular pacing; Parikshit S. Sharma, Pugazhendhi Vijayaraman & Kenneth A. Ellenbogen; Nature Reviews Cardiology, 27 June 2019

Deep Negative Deflection in Unipolar His-Bundle Electrogram as a Predictor of Excellent His-Bundle Pacing Threshold Postimplant; Toshiaki Sato , Kyoko Soejima , Akiko Maeda , Takato Mohri , Mika Tashiro , Yuichi Momose , Michitsugu Komeda , Noriko Nonoguchi , Kyoko Hoshida , Yosuke Miwa , Akiko Ueda , Ikuko Togashi, Circulation: Arrhythmia and Electrophysiology, Vol. 12, No. 6, https://doi.org/10.1161/CIRCEP.119.007415

Low Fluoroscopy Permanent His Bundle Pacing Using Electroanatomic Mapping; Parikshit S. Sharma , Henry D. Huang , Richard G. Trohman , Angela Naperkowski , Kenneth A. Ellenbogen , Pugazhendhi Vijayaraman; Originally published1 Feb 2019https://doi.org/10.1161/CIRCEP.118.006967Circulation: Arrhythmia and Electrophysiology. 2019;12

Direct Visualization of the His Bundle Pacing Lead Placement by 3-Dimensional Electroanatomic Mapping; Michael V. Orlov , Ioannis Koulouridis , AJ Monin , David Casavant , Mikhail Maslov , Aharon Erez , Amy Hicks , Joe Aoun , John V. Wylie; Circulation: Arrhythmia and Electrophysiology, Vol. 12, No 2, 11 Feb 2019

Novel Method for Assessment of His Bundle Pacing Morphology Using Near Field and Far Field Device Electrograms; Aditya Saini , Nicholas J. Serafini , Shawn Campbell , William B. Waugh , Ryan Zimberg , Todd J. Sheldon , Jordana Kron , Gautham Kalahasty , Santosh K. Padala , Richard Trohman , Richard K. Shepard , Jayanthi N. Koneru , Pugazhendhi Vijayaraman , Kenneth A. Ellenbogen , Parikshit S. Sharma; Circulation: Arrhythmia and Electrophysiology; February 2019 – Volume 12, Issue 2

Programmed His Bundle Pacing; Marek Jastrzębski , Paweł Moskal , Agnieszka Bednarek , Grzegorz Kiełbasa , Pugazhendhi Vijayaraman , Danuta Czarnecka; Circulation: Arrhythmia and Electrophysiology, 1 Feb 2019, Vol. 12, No 2, https://doi.org/10.1161/CIRCEP.118.007052

Device Programming for His Bundle Pacing; Haran Burri , Daniel Keene , Zachary Whinnett , Francesco Zanon Pugazhendhi Vijayaraman; Originally published 6 Feb 2019https://doi.org/10.1161/CIRCEP.118.006816Circulation: Arrhythmia and Electrophysiology. 2019;12

Permanent His-bundle pacing in patients with prosthetic cardiac valves; Parikshit S.Sharma, MD, MPH*, Faiz A.Subzposh, MD†, Kenneth A.Ellenbogen, MD,FHRS*, Pugazhendhi Vijayaraman, MD,FHRS†, *Virginia Commonwealth University Medical Center, Richmond, Virginia, and †Geisinger Heart Institute, Wilkes-Barre, Pennsylvania; J of Electrocardiology, Published online: July 11, 2016

Electrophysiologic Insights Into Site of Atrioventricular Block: Lessons From Permanent His Bundle Pacing; Pugazhendhi Vijayaraman, Angela Naperkowski, Kenneth A. Ellenbogen and Gopi Dandamudi; Geisinger Wyoming Valley Medical Center & Virginia Commonwealth University Health System; JACC: Clinical Electrophysiology, Vol 1, Issue 6, Dec 2015

Synchronous ventricular pacing with direct capture of the atrioventricular conduction system: Functional anatomy, terminology, and challenges: Siva K. Mulpuru, MD, FHRS, Yong-Mei Cha, MD, FHRS, Samuel J. Asirvatham, MD, FHRS; Heart Rhythm, November 2016 Volume 13, Issue 11, Pages 2237–2246

Anatomical approach to permanent His bundle pacing: Optimizing His bundle capture; Pugazhendhi Vijayaraman, MD,a, Gopi Dandamudi, MD,b; a Geisinger Heart Institute, Wilkes Barre, PA, b Indiana University School of Medicine, Indianapolis, IN; Journal of Electrocardiology 49 (2016) p 649 – 657

How to Perform Permanent His Bundle Pacing: Tips and Tricks; Gopi Dandamudi M.D.,* Pugazhendhi Vijayaraman, MD., F.H.R.S.ˆ *Indiana University School of Medicine, Indianapolis, ˆGeisinger Heart Institute, Wilkes-Barre, Pennsylvania; DOI: 10.1111/pace.12904

Step-wise Approach to Permanent His Bundle Pacing; Daniel Lustgarten, MD, PhD, FHRS; The University of Vermont School of Medicine, Department of Cardiology, Burlington, VT; The Journal of Innovations in Cardiac Rhythm Management, 7 (2016), 2313–2321

How to perform permanent His bundle pacing in routine clinical practice; Dandamudi G, MD, FHRS*, Vijayaraman P, MD, FHRS**, *Indiana University School of Medicine, Indianapolis, IN, and **Geisinger Wyoming Valley Hospital, Wilkes-Barrie, PA; 2016 Heart Rhythm Society, June 2016 Volume 13, Issue 6, Pages 1362–1366 http://www.heartrhythmjournal.com/article/S1547-5271(16)30084-4/abstract

The Complexity of the His Bundle: Understanding Its Anatomy and Physiology through the Lens of the Past and the Present; Gopi Dandamudi M.D.,* Pugazhendhi Vijayaraman, MD., F.H.R.S.** *Indiana University School of Medicine, Indianapolis, **Geisinger Heart Institute, Wilkes-Barre, Pennsylvania; 20 September 2016, DOI: 10.1111/pace.12925

Full text article on implant procedure:
Permanent His-bundle Pacing is Feasible, Safe, and Superior to Right Ventricular Pacing in Routine Clinical Practice; Parikshit S. Sharma, MD, MPH; Gopi Dandamudi, MD, FHRS; Angela Naperkowski, RN, FHRS, CCDS, CEPS (Geisinger Wyoming Valley Medical Center, Wilkes Barre, Pennsylvania); Jess W.Oren, MD; Randle H.Storm, MD, FHRS (Geisinger Medical Center, Danville, Pennsylvania); Kenneth A. Ellenbogen, MD, FHRS (Virginia Commonwealth University Medical Center, Richmond, Virginia); Pugazhendhi Vijayaraman, MD, FHRS (Geisinger Wyoming Valley Medical Center, Wilkes Barre, Pennsylvania); Heart Rhythm, Vol. 12, No 2, February 2015; prior, Heart Rhythm Society, Scientific Sessions, 2014

Permanent His-Bundle Pacing: Case Studies; Pugazhendhi Vijayaraman, M.D.* and Gopi Dandamudi, M.D.†; *Division of Cardiac Electrophysiology, Geisinger Heart Institute, Wilkes-Barre, Pennsylvania, †Indiana University School of Medicine, Indianapolis, Indiana; PACE 2016; 00:1–8

Electrophysiological observations of acute His bundle injury during permanent His bundle pacing; Vijayaraman, P. MD, FHRS, a, Dandamudi, G. MD,b Ellenbogen, K. MDc; a Geisinger Wyoming Valley Medical Center, Wilkes-Barre, PA,, b Indiana University, Indianapolis, IN,c Virginia Commonwealth University Health System, Richmond, VA; Journal of Electrocardiology 49 (2016) p. 664 – 669

Acute His-Bundle Injury Current during Permanent His-Bundle Pacing Predicts Excellent Pacing Outcomes; Vijayaraman P, Dandamudi G, Worsnick S, Ellenbogen KA. 1Department of Cardiac Electrophysiology, Geisinger Heart and Vascular Institute, Wilkes-Barre, Pennsylvania; Pacing Clinical Electrophysiology, 2015 Jan 14. doi: 10.1111/pace.12571

Direct Implantation of Permanent His Bundle Pacing Lead in Patients with Complete Heart Block Without a Mapping Catheter or a Back-up Right Ventricular Lead: Feasibility and One year Follow-up; Naperkowski, Angela, CEPS, Sharma, Parikshit, MD, MPH, Dandamudi, Gopi, MD,FHRS, Ellenbogen, Kenneth, MD, FHRS, and Vijayaramen, Pugazhendhi, MD, Geisinger Wyoming Valley Medical Center, Wilkes-Barrie, PA, Virginia Commonwealth University Health System, Richmond, VA; Heart Rhythm Society, Scientific Sessions, 2013

Safety And Feasibility of Permanent His Bundle Pacing Without a Guiding Mapping Catheter or a Ventricular Lead in Routine Clinical Practice; Sharma, Parikshit, MD, MPH, Naperkowski, Angela,RN, Dandamudi, Gopi, MD, FHRS, Ellenbogen, Kenneth, MD, FHRS and Vijayaraman, Pugazhendhi, MD, FHRS, Wright Center for GME, Scranton, PA, Geisinger Wyoming Valley Medical Center, Wilkes-Barrie, PA, Virginia Commonwealth University Health System, Richmond, VA; Heart Rhythm Society, Scientific Sessions, 2013

Direct His bundle and Parahisian Cardiac Pacing; Zanon, F, M.D., Barold, M.D.; A.N.E., April 2012, Vol. 17, No. 2

His Bundle Injury Current during Implantation of Permanent His Bundle Pacing Lead Predicts Excellent Pacing Outcomes; Vijayaramen, Pugazhendhi, MD, FHRS, Dandamudi, Gopi, MD, FHRS, Worsnick, Sarah, CCDS and Ellenbogen, Kenneth, MD, FHRS. Guisinger Health System, Geisinger Wyoming Valley Medical Center, Wilkes-Barrie, PA, Medical College of Virginia, Richmond, VA; Heart Rhythm Society, Scientific Sessions, 2014

Right Ventricular Pacing as Backup to His Bundle Pacing to Minimize Battery Drain; Khoo, Clarence, MD, Bennett, Matthew, MD, Lemaitre, MD, Chakrabarti, Santabhanu, MD, Deyell, Marc, MD, Andrade, Jason, MD, Karhn, Andrew, MD, and Tung, Stanley, MD, University of British Columbia, Vancouver, BC, Canada; Heart Rhythm Society, Scientific Sessions, 2013

Permanent His Bundle Pacing in Patients with Advanced Heart Block: Single Center Experience in Unselected Patients Without Mapping Catheter or Back-Up RV Pacing Lead; Vijayaramen, Pugazhendhi, MD, FHRS, Naperkowski, Angela, CCDS, Dandamudi, Gopi, MD,FHRS and Ellenbogen, Kenneth, MD, FHRS. Guisinger Health System, Geisinger Wyoming Valley Medical Center, Wilkes-Barrie, PA, Medical College of Virginia, Richmond, VA.; Heart Rhythm Society, Scientific Sessions, 2014

Safety and Performance of a System Specifically Designed for Selective Site Pacing; Zanon, Francesco, M.D., Svetlych, M.D., Occhetta, Eraldo, M.D., Catanzraiti, Dominico, M.D., Cantu, Francesco, M.D., Padeletti, Luigi, M.D., Santini, Massimo, M.D., Sentore, Gaetano, M.D., Comisso, Jennifer, M.S. Varbaro, Annamaria, M.S., Denaro, Alessandra, M.S.; Pacing and Clinical Electrophysiology, Volume 34, Issue 3, pages 339–347, March 2011

A Feasible Approach for Direct His-Bundle Pacing Using a new Steerable Catheter to Facilitate Precise Lead Placement; Zanon, Francesco, Enrico Baracca, Silvio Aggio, Gianni Pastore, Granziano Boaretto, Paola Cardano, Tiziana Marotta, Gianluca Rigatelli, Mariapalo Galasso, Mauro Carraro, Pietro Zonzin; JCE January 2006; 17:29-33

Permanent Para-Hisian Pacing is Feasible Without a Guiding Electrophysiology Catheter; Pugazhendhi Vijayaraman, MD, James Bonczek, RRT, Angela Naperkowski, RN and Kenneth A. Ellenbogen, MD. Geisinger Wyoming Valley Medical Center, Wilkes-Barre, PA, Medical College of Virginia, Richmond, VA; Heart Rhythm Society, Scientific Sessions, 2014

Feasibility of Direct His-Bundle Pacing Without and EP Market To Guide the Correct Placement of the FSREW Permanent Lead; Francesci Zanon, MD, Gianni Pastore, MD, Enrico Baracca, MD, Silvio Aggio, MD, Raffagnato Paola, RN, Antonalla Tiribello, RN, Graziano Boaretto, RN, Loris, Roncon, MD Division of Cardiology, General Hospital, Rovigo, Italy; Heart Rhythm 2009, May 15, 2009

Can patients at risk of pacemaker induced heart failure be identified at time of implant or beyond?

Impact of simple electrocardiographic markers as predictors for deterioration of left ventricular function in patients with frequent right ventricular apical pacing; Hayashi Y¹, Takaqi M², Kakihara J¹, Sakamoto S¹, Tatsumi H¹, Doi A¹, Iwata S¹, Sugioka K¹, Yoshiyama M¹, ¹Department of Medicine, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan, ² Department of Cardiovascular Medicine, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan. m7424580@msic.med.osaka-cu.ac.jp.; Heart Vessels, 2017 Sep 26, doi: 10.1007/s00380-017-1052-x. [Epub ahead of print]1

Three-dimensional echocardiography with left ventricular strain analyses helps earlier prediction of right ventricular pacing-induced cardiomyopathy; Babu NMS, Srinath SC, Lahiri A, Chase D, John B, Roshan J; Department of Cardiology, Christian Medical College, Vellore 632004, IndiaaIndia; J Saudi Heart Assoc. 2018 Apr;30(2):102-107. doi: 10.1016/j.jsha.2017.06.001. Epub 2017 Jun 12.

Long-term follow up of clinical His bundle pacing

Permanent His-bundle pacing: Long-term lead performance and clinical outcomes; Pugazhendhi Vijayaraman, Angela Naperkowski, Faiz A Subzposh, Mohamed Abdelrahman, Parikshit S Sharma, Jess W Oren, Gopi Dandamudi, Kenneth A Ellenbogen; HeartRhythm, Vol 15, Issue 5, P696-702, May 01, 2018, DOI: https://doi.org/10.1016/j.hrthm.2017.12.022

Clinical Outcomes Of Selective Versus Nonselective His Bundle Pacing; Dominik Beer, Parikshit S. Sharma, Faiz A. Subzposh, Angela Naperkowski, Grzegorz Marcin Pietrasik, Brendan Durr, Maria Qureshi, Ragesh Panikkath, Mohamed Abdelrahman, Brent A. Williams, Jillian L. Hanifin, Ryan Zimberg, Kelly Austin, Brooke Macuch, Richard G. Trohman, Erin A. Vanenkevort, Gopi Dandamudi and Pugazhendhi Vijayaraman; JACC: Clinical Electrophysiology, May 2019, DOI: 10.1016/j.jacep.2019.04.008

Permanent His bundle pacing: Electrophysiological and echocardiographic observations from long‐term follow‐up; Pugazhendhi Vijayaraman MD, FHRS, Gopi Dandamudi MD, FHRS, Daniel Lustgarten MD, FHRS, Kenneth A Ellenbogen MD, FHRS; PACE, Vol 40, Issue7 July 2017 Pages 883-891

Long-term His-Bundle Pacing and Cardiac Function; Scheinman, Melvin M., Leslie A. Saxon; Circulation 2000; 101:836-837

What was the early research leading to His bundle pacing?

The 50 Year Anniversary of the His Bundle Recording and Pacing in Clinical Medicine; Benjamin J. Scherlag PhD, Sunny S. Po, MD, PhD, Heart Rhythm Institute and Section of Cardiovascular Diseases, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; DOI: https://doi.org/10.1016/j.hrthm.2019.02.014, Heart Rhythm Journal

Pervenous Pacing of the Specialized Conducting System in Man; O S Narula, B J Scherlag, P Samet; Jan 1970, https://doi.org/10.1161/01.CIR.41.1.77, Circulation 1970, 41:77–87

Re-evaluation of the atrial contribution to ventricular function: Study using His bundle pacing; Bernard D.KosowskyM.D., Benjamin J.ScherlagPh.D., Anthony N.DamatoM.D; The American Journal of Cardiology, Volume 21, Issue 4, April 1968, Pages 518-524

History of His Bundle Pacing; Dandamudi G(1), Vijayaraman P(2), (1)Indiana University School of Medicine, Indianapolis, IN. Electronic address:gdandamu@iu.edu. (2)Geisinger Heart Institute, Wilkes-Barre, PA; Journal of Electrocardiol. 2016 Sep 24

Functional aspects of His bundle physiology and pathophysiology: Clinical implications; Benjamin. Scherlag, PhD, Ralph Lazzara, MD Heart Rhythm Institute, Division of Cardiology, Department of Medicine, Oklahoma University Health Sciences Center, Oklahoma City, OK; Journal of Electrocardiology (2016)

Wilhelm His Junior and his bundle; Robert H. Anderson, BSc, MD,a, Shumpei Mori, MDb; a Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom, b Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan; Journal of Electrocardiology 49 (2016) 637 – 643

His bundle pacing: Initial experience and lessons learned; Deshmukh A, MD a, Deshmukh, P, MD b, Department of Medicine, University of Chicago, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, b Arrhythmia Center, Robert Packer Hospital, 1 Guthrie Square, Sayre, PA; Journal of Electrocardiology 49 (2016) 658 – 663

The Muscular Reactions of the Mammalian Ventricles to Artificial Surface Stimulation; Wiggers C.; Physiological Laboratory, Western Reserve University, School of Medicine, Cleveland, OH; April 20, 1925

Validation of Criteria for Selective His Bundle and Para-Hisian Permanent Pacing; Cantù, F.; De Filippo, P.; Cardano, P.; De Luca, A.; Gavazzi, A; Pacing & Clinical Electrophysiology; Dec 2006, Vol. 29 Issue 12, p1326-1333, 8p, 1 chart, 5 graphs; DOI: 10.1111/j.1540-8159.2006.00543.x; (AN 23481745) HRS Abstracts 2009

Direct His-Bundle Pacing: Present and Future; Deshmukh PM, Romanyshyn M; PACE, 2004; 27 [Pt.II]:862-70.

His and para-His Pacing in AV Block: Feasibility and Electrocardiac Findings; Kronborg, M., Mortensen, P., Gerdes, J., Jensen, H., Nielsen,J; Journal of Interventional Electrophysiology, 2011, 31:255-262

Future Easy and Physiological Cardiac Pacing; Occhetta E, Bortnik M, Marino P World; Journal of Cardiology, Vol. 3, Issue 1, Jan 26, 2011

Excitation of the Intrinsic Conduction System Through His and Interventricular Septal Pacing; Laske TG, Skadsberg ND, Hill AJ, Klein GJ, Iaizzo PA; PACE, April 2006; 29(4):397-405

Feasibility of His Bundle Pacing as an Alternative Pacing Site: Measurement of His Refractoriness; Gula, Lorne, Geoffrey M. Trim, Andrew D Krahn, Allan C. Skanes, Raymond Yee, George J Klein; Journal of Interventional Cardiac Electrophysiology, 2005; 12: 69-73

A Technique For Stable His-bundle Recording and Pacing: Electrophysiological and Hemodynamic Correlates; Mabo P, Scherlag BJ, Munsif A, Otomo K, Lazzara R.; Pacing Clinical Electrophysiology 1995; 18:1894-901

Septal His-Purkinje Ventricular Pacing in Canines: A New Endocardial Electrode Approach; Karpawich PP, Gates J, Stokes KB Pacing Clinical Electrophysiology 1992; 15:2011-5.

Septal Ventricular Pacing in the Immature Canine Heart: A New Perspective; Karpawich PP, Justice CD, Chang CH, Gause CY, Kuhns LR;American Heart Journal; 1991;121:827-33.

Relative Importance of Activation Sequence Compared to Atrioventricular Synchrony in Left Ventricular Function; Rosenqvist M, Isaaz K, Botvinick EH, Dae MW, Cockrell J, Abbott JA, Schiller NB, Griffin JC; American Journal of Cardiology; 1991;67:148-56.

Atrial Versus Ventricular Pacing in Sinus Node Disease: a Treatment Comparison Study; Rosenqvist M, Brandt J, Schuller H.; American Heart Journal; 1986;111:292-7

Selective Versus non-Selective His Bundle Pacing; Williams DO, Sherlag BJ, Hope RR, El-Sherif N, Lazzara R, Samet P; Cardiovascular Research 1976; 10(1):91-100

The Effect of Ventricular Activation Sequence on Cardiac Performance During Pacing; Rosenqvist M., Bergfeldt L., Haga Y., et al; PACE, 1996; 19:1279-86

His Bundle Pacing: Great in Theory, But Difficult in Practice; Garrote J; Revista Española de Cardiología; 2006; 59(6):534-6.

Intracardiac Echocardiography-Guided His Bundle Pacing and Atrioventricular Nodal Ablation; Lixue Yin; Laske, Timothy G.; Rakow, Nancy; Li Cai; Williams, Terrell; Chunmei Li; Yong Zhao; Yan Deng; Lijian Chen; Shuang Li; Shan Wang; Changquong Zheng; Deyu Li; Tianfun Wang; Yi Zheng; Pacing & Clinical Electrophysiology, May 2008, Vol. 31 Issue 5, p536-542, 7p, 2 charts, 1 graph, 3 bw; DOI: 10.1111/j.1540-8159.2008.01037.x; (AN 31768456)

Hemodynamic Evaluation of Direct His-Bundle and Parahisian Pacing; Robert H. Hoyt, MD, Richard H. Marcus, MD, Brian T. McHenry, MS and Michelle M. Fedewa, PhD. Iowa Heart Center, Des Moines, IA, Medtronic, Inc., Minneapolis, MN; Heart Rhythm 2009, Poster Session V, May 15, 2009

His-bundle pacing news, for better pacemaker patient outcomes

His-bundle pacing news, for better pacemaker patient outcomes

His-Bundle and Left Bundle Branch Pacing Papers

What was the early research leading to His bundle pacing?